Results 61 to 70 of about 11,395,261 (251)

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

Mass-loss Rate of Highly Evolved Stars in the Magellanic Clouds

open access: yesThe Astrophysical Journal Supplement Series
Asymptotic giant branch stars (AGBs) and red supergiant stars (RSGs) exhibit significant mass-loss phenomena and are considered important sources of interstellar dust.
Jing Wen   +5 more
doaj   +1 more source

Sulfate Corrosion Resistance and Microstructure Characteristics of Iron Tailings Concrete

open access: yesKuangchan zonghe liyong
This is an article in the field of ceramics and composites. Mechanical properties and durability of sodium sulfate solution corrosion of iron tailings concrete are developed.
Qing MIAO, Jian CHANG, Boyi SUN
doaj   +1 more source

The microbiome in human skin aging

open access: yesFEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana   +3 more
wiley   +1 more source

Rate

open access: yes, 2008
Fig.4 Comparison of loss rate using global SRM vs. ASRM 4 ASRM SRM
Loss Rate
core  

Minimizing blood loss and transfusion rate in laparoscopic liver surgery: a review

open access: yes, 2023
Laparoscopic liver resection has become a standard practice in many surgical wards in elective liver surgery, due to its positive impact on reducing hospital stay and postoperative complications, including lower blood loss and transfusion rate.
Major, Piotr   +9 more
core   +1 more source

Autophagy and mitophagy in pancreatic β‐cell homeostasis and their involvement in diabetes pathophysiology

open access: yesFEBS Letters, EarlyView.
This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee   +2 more
wiley   +1 more source

Mass observation / by Mass Observation.

open access: yes, 1945
Electronic reproduction. Canberra, A.C.T.
Mass-Observation.
core  

The Effect of Varying Mass Loss Rate on the Initial-Final Mass Relation of Massive Stars

open access: yes, 2021
: Stellar mass loss has a high impact on the overall evolution of a star. The amount of mass lost during a star’s lifetime dictates which remnant will be left behind and how the circumstellar environment will be affected.

core  

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