Results 51 to 60 of about 3,125,229 (337)

Mass Shootings and the Media: How Race and Ethnicity Influence Media Coverage [PDF]

open access: yes, 2017
Topics related to crime and the criminal justice system comprise a majority of topics discussed in the media. This study explores how media coverage of mass shootings varies based on the racial or ethnic identity of the shooter.
Wheeler, Emily
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1

open access: yesMolecular Oncology, EarlyView.
Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero   +8 more
wiley   +1 more source

Measuring Media Political Bias in Slovak TV News Programmes During 2023 Parliamentary Elections

open access: yesEconomics and Culture
The main objective of this study is to assess the political bias present in the news programmes broadcast by two private TV stations – TV Markíza and TV JOJ – and the public service TV station Jednotka during the campaign period leading up to the 2023 ...
Furtáková Lucia   +3 more
doaj   +1 more source

Structured Deliberative Gossip and Nigerian Government in the Digital Era

open access: yesEthiopian Journal of the Social Sciences and Humanities
Active citizen participation in governance, openness and prompt provision of adequate information for the public to make informed decision is crucial for any meaningful development to be achieved.
Desmond Onyemechi Okocha, Jesse Ishaku
doaj   +1 more source

The Effects of Media Coverage on Mass Shootings in the United States [PDF]

open access: yes, 2018
This paper discusses the effects media coverage and media portrayal have on mass shootings in the United States. As the occurrences of mass shootings in the United States have increased, the depiction of these events through news outlets, media stories ...
Chen, Lisa
core   +1 more source

Nicotinamide N‐methyltransferase promotes drug resistance in lung cancer, as revealed by nascent proteomic profiling

open access: yesMolecular Oncology, EarlyView.
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou   +5 more
wiley   +1 more source

Body Image Perception: Adolescent Boys and Avatar Depiction in Video Games [PDF]

open access: yes, 2016
Research on mass media’s impact on body image has mostly been focused on females thus far. Of the little research that has been done on male body image, most of it has been focused on adult males, and therefore the effect of mass media on adolescent boys’
Raman, Usha
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

open access: yesMolecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak   +8 more
wiley   +1 more source

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