Results 61 to 70 of about 3,116,970 (291)

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Theory and Applications of Web 3.0 in the Media Sector

open access: yesFuture Internet, 2023
We live in a digital era, with vast technological advancements, which, among others, have a major impact on the media domain. More specifically, progress in the last two decades led to the end-to-end digitalization of the media industry, resulting in a ...
Charalampos A. Dimoulas, Andreas Veglis
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Measuring Media Political Bias in Slovak TV News Programmes During 2023 Parliamentary Elections

open access: yesEconomics and Culture
The main objective of this study is to assess the political bias present in the news programmes broadcast by two private TV stations – TV Markíza and TV JOJ – and the public service TV station Jednotka during the campaign period leading up to the 2023 ...
Furtáková Lucia   +3 more
doaj   +1 more source

Structured Deliberative Gossip and Nigerian Government in the Digital Era

open access: yesEthiopian Journal of the Social Sciences and Humanities
Active citizen participation in governance, openness and prompt provision of adequate information for the public to make informed decision is crucial for any meaningful development to be achieved.
Desmond Onyemechi Okocha, Jesse Ishaku
doaj   +1 more source

Search Engine Optimization

open access: yesFuture Internet, 2019
The introduction of the World Wide Web (WWW), 25 years ago, has considerably altered the manner in which people obtain information [...]
Andreas Veglis, Dimitrios Giomelakis
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Mass Media and Environmental Risk: Seven Principles [PDF]

open access: yes, 1994
Dr. Sandman suggests that, when spokespersons for risk sources are inept in conveying their messages, they and we pay heavily for their ...
Sandman, Peter M.
core   +2 more sources

Why Mass Media Matter to Planning Research: The Case of Megaprojects

open access: yes, 2012
This article asks how planning scholarship may effectively gain impact in planning practice through media exposure. In liberal democracies the public sphere is dominated by mass media.
Flyvbjerg, Bent
core   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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