Results 11 to 20 of about 14,736,719 (207)

Interactive effects of joint angle, contraction state and method on estimates of achilles tendon moment arms [PDF]

open access: yes, 2013
Copyright @ 2013 Human Kinetics, IncThe muscle-tendon moment arm is an important input parameter for musculoskeletal models. Moment arms change as a function of joint angle and contraction state and depend on the method being employed.
Blazevich, AJ   +4 more
core   +6 more sources

Modeling of Mass Transfer and Reactions with the Moment Method [PDF]

open access: yes, 2015
In chemical engineering field, mass transfer and reaction process models are needed in many stages of process research and design. These models usually consist of systems of partial differential equations.
Liu, Zheng
core   +1 more source

An algorithm for LES of premixed compressible flows using the Conditional Moment Closure model [PDF]

open access: yes, 2011
A novel numerical method has been developed to couple a recent high order accurate fully compressible upwind method with the Conditional Moment Closure combustion model. The governing equations, turbulence modelling and numerical methods are presented
Bilger, R. W.   +7 more
core   +1 more source

Conditional moment closures for turbulent reacting flows [PDF]

open access: yes, 2003
Mathematical modelling of the turbulent combustion process is becoming increasingly applied in calculations to assist in the design and analysis of practical combustion devices for efficiency-improvement and emission reduction. The current requirement to
Woolley, Robert Michael
core   +6 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

Moving the Weber fraction: the perceptual precision for moment of inertia increases with exploration force [PDF]

open access: yes, 2012
How does the magnitude of the exploration force influence the precision of haptic perceptual estimates? To address this question, we examined the perceptual precision for moment of inertia (i.e., an object’s ‘‘angular mass’’) under different force ...
Kingma, I.   +20 more
core   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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