Results 71 to 80 of about 158,369 (302)

AN ALGORITHM FOR COMPACT FIXED-POINT IMPLEMENTATION OF DIGITAL CONTROLLERS [PDF]

open access: yesНаучно-технический вестник информационных технологий, механики и оптики, 2018
We propose and study the algorithm of digital controllers implementation in fixed-point arithmetic based on the adaptive selection of a discrete transform and a discrete operator (z- or δ-operator).
T. I. Karimov   +3 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

The two-mass contributions to the three-loop massive operator matrix elements $${\widetilde{A}}_{Qg}^{(3)}$$ and $${\Delta \widetilde{A}}_{Qg}^{(3)}$$

open access: yesJournal of High Energy Physics
We calculate the two-mass three-loop contributions to the unpolarized and polarized massive operator matrix elements $${\widetilde{A}}_{Qg}^{(3)}$$ and $${\Delta \widetilde{A}}_{Qg}^{(3)}$$ in x-space for a general mass ratio by using a semi-analytic ...
J. Ablinger   +5 more
doaj   +1 more source

Revisiting the connection of baryon number, lepton number, and operator dimension

open access: yesPhysics Letters B
The effects of heavy new particles beyond the Standard Model can be conveniently captured through higher-dimensional effective operators. As noted long ago by Weinberg, the amount of baryon and lepton number an operator can carry is intricately connected
Julian Heeck, Diana Sokhashvili
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Quantum dynamics of a driven parametric oscillator in a Kerr medium

open access: yesScientific Reports, 2023
In this paper, we first analyze a parametric oscillator with both mass and frequency time-dependent. We show that the evolution operator can be obtained from the evolution operator of another parametric oscillator with a constant mass and time-dependent ...
E. Bolandhemmat, F. Kheirandish
doaj   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Static analysis of the vibration protection mechanism of the human operator seat of a ground machine [PDF]

open access: yesНаучно-технический вестник Брянского государственного университета
Ground transport and technological machines are being improved, which leads to an increase in their power, speed, vibrations and impacts. Vibrations have a negative effect on the technical condition of the machine, health and performance of the operator.
Korytov M.S.   +2 more
doaj   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

open access: yesMolecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi   +7 more
wiley   +1 more source

Chiral condensate from the twisted mass Dirac operator spectrum. [PDF]

open access: yes, 2013
We present the results of our computation of the dimensionless chiral condensate r 0Σ1/3 with N f = 2 and N f = 2 + 1 + 1 flavours of maximally twisted mass fermions.
Jansen, Karl   +5 more
core   +1 more source

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