Results 121 to 130 of about 7,834,536 (290)

Heave Response Control of a Semisubmersible by Passive Dampers

open access: yes한국해양공학회지
Semisubmersibles, deployed offshore in the deep sea experience undesired motion. Large heave motion is one of the concerns and requires mitigation for operational safety.
Ajaya Kumar Das   +1 more
doaj   +1 more source

7.33 S94-027293 Mass Ratio, Proto. accel. & force

open access: yes
A view of several instruments, noted Mass Ratio, Proto. accel.

core  

Gravitational waves from extreme-mass-ratio inspirals in equatorially eccentric orbits

open access: yes, 2014
Based on the numerical frame which combines the effective one-body (EOB) dynamics with the frequency-domain Teukolsky equation, we calculate the waveforms from the extreme-mass-ratio inspirals (EMRIs) with equatorially eccentric orbits.
Han, Wen-Biao
core  

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Primordial extreme mass-ratio inspirals

open access: yesPhysics Letters B
The coalescence of stellar-mass primordial black holes (PBHs) might explain some of the gravitation waves (GWs) events detected by LIGO-Virgo-KAGRA. On the other hand, observational hints for supermassive PBHs (SMPBHs) have been accumulated.
Hai-Long Huang   +2 more
doaj   +1 more source

mass-to-charge ratio

open access: yes, 2014
Citation: 'mass-to-charge ratio' in the IUPAC Compendium of Chemical Terminology, 3rd ed.; International Union of Pure and Applied Chemistry; 2006. Online version 3.0.1, 2019. 10.1351/goldbook.M03752 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Optimisation Design and Damping Effect Analysis of Large Mass Ratio Tuned Mass Dampers

open access: yesShock and Vibration, 2019
Under harmonic load and random stationary white noise load, the existing fitting formulas are not suitable for calculating the optimal parameters of large mass ratio tuned mass dampers (TMDs).
Ying-jie Kang, Ling-yun Peng
doaj   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

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