Results 171 to 180 of about 12,854,723 (342)
SIRT4 positively regulates autophagy via ULK1, but independently of HDAC6 and OPA1
Cells expressing SIRT4 (H161Y), a catalytically inactive mutant of the sirtuin SIRT4, fail to upregulate LC3B‐II and exhibit a reduced autophagic flux under stress conditions. Interestingly, SIRT4(H161Y) promotes phosphorylation of ULK1 at S638 and S758 that are associated with inhibition of autophagy initiation.
Isabell Lehmkuhl +13 more
wiley +1 more source
The Associations Between Chronic Active Lesions and White Matter Disease: A 7 Tesla Imaging Study
ABSTRACT Background The relationship between paramagnetic rim lesions (PRLs) and surrounding normally appearing white matter (NAWM) disease, potentially contributory to the associations seen between PRLs and clinical impairment, is underexplored. Objectives To assess whether PRLs correlate with a greater degree of NAWM injury in early MS.
Ellie McCluey +17 more
wiley +1 more source
Constraining the EdGB theory with extreme mass-ratio inspirals
The Einstein-dilaton-Gauss–Bonnet (EdGB) theory is a modified theory of gravity which include a scalar field to couple with the higher order curvature terms.
Jing Tan +3 more
doaj +1 more source
Total and Regional Fat/Muscle Mass Ratio and Risks of Incident Cardiovascular Disease and Mortality. [PDF]
Zhou R +6 more
europepmc +1 more source
Teaching Research on the Experimental Methods of Calculating the Charge-to-Mass Ratio of Electron [PDF]
Xiaojuan Niu +3 more
openalex +1 more source
Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski +13 more
wiley +1 more source
Extreme mass-ratio inspiral around the horizonless massive object
In this paper, we calculated the extreme mass-ratio inspiral (EMRI) waveform radiated from a binary composed of a massive horizonless object (MHO) and a compact object (CO), where CO is spiraling on a circular equatorial orbit around the MHO.
Tieguang Zi, Liangliang Ren, Jun Cheng
doaj +1 more source
Simulations of extreme-mass-ratio inspirals using pseudospectral methods
Priscilla Canizares +3 more
openalex +1 more source

