Results 171 to 180 of about 4,338,110 (346)

CDK5 interacts with MST2 and modulates the Hippo signalling pathway

FEBS Open Bio, Volume 15, Issue 4, Page 647-660, April 2025.
By using a yeast‐two‐hybrid system, immune precipitation and a proteomics approach, we identify a novel interaction between CDK5 and MST2, which modulates the mechano‐sensitive Hippo signalling pathway in a liver tumour cell line. MST2 (STK3) is a major upstream kinase in the Hippo signalling pathway, an evolutionary conserved pathway in regulation of ...
Mehak Passi, Jan B. Stöckl, Thomas Fröhlich, Simone Moser, Angelika M. Vollmar, Stefan Zahler   +5 more
wiley   +1 more source

Constraining the EdGB theory with extreme mass-ratio inspirals

European Physical Journal C: Particles and Fields
The Einstein-dilaton-Gauss–Bonnet (EdGB) theory is a modified theory of gravity which include a scalar field to couple with the higher order curvature terms.
Jing Tan, Jian-dong Zhang, Hui-Min Fan, Jianwei Mei   +3 more
doaj   +1 more source

Total and Regional Fat/Muscle Mass Ratio and Risks of Incident Cardiovascular Disease and Mortality. [PDF]

J Am Heart Assoc, 2023
Zhou R, Chen HW, Lin Y, Li FR, Zhong Q, Huang YN, Wu XB.   +6 more
europepmc   +1 more source

FAM136A depletion induces mitochondrial stress and reduces mitochondrial membrane potential and ATP production

FEBS Open Bio, Volume 15, Issue 5, Page 738-753, May 2025.
FAM136A depletion upregulated ROS production, reduced mitochondrial membrane potential (ΔΨ) and ATP production, and upregulated expression of PCK1, PCK2, HMGCS1, and HMGCS2. The expression of both TOMM22 and TOMM20 was also upregulated. FAM136A depletion reduced HCCS that produce holocytochrome c by combining heme to apocytochrome c, and reduced the ...
Yushi Otsuka, Masato Yano
wiley   +1 more source

In-Season Longitudinal Hydration/Body Cell Mass Ratio Changes in Elite Rugby Players. [PDF]

Sports (Basel), 2023
Cebrián-Ponce Á, Petri C, Izzicupo P, Micheli ML, Cortis C, Fusco A, Carrasco-Marginet M, Mascherini G.   +7 more
europepmc   +1 more source

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, Volume 15, Issue 5, Page 836-855, May 2025.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

A determination of the mass ratios and parallaxes of Castor and 70 Ophiuchi

, 1943
Erik Holmberg
openalex   +1 more source

Meson to Proton Mass Ratios

Physical Review, 1951
Barkas, Walter H., Smith, F.M., Gardner, Eugene   +2 more
openaire   +3 more sources

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, Volume 15, Issue 5, Page 773-792, May 2025.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Anticipated correlation between lean body mass to visceral fat mass ratio and insulin resistance: NHANES 2011-2018. [PDF]

Front Endocrinol (Lausanne), 2023
Shao Y, Li L, Zhong H, Wang X, Hua Y, Zhou X.   +5 more
europepmc   +1 more source