Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Purpose: To survey medical institutions in Korea that conduct chest low-dose computed tomography (LDCT) scan prior to introduction of the national lung cancer screening (LCS) project.
Jae Gu Oh +4 more
doaj +1 more source
Improved design of electrophoretic equipment for rapid sickle-cell-anemia screening [PDF]
Effective mass screening may be accomplished by modifying existing electrophoretic equipment in conjunction with multisample applicator used with cellulose-acetate-matrix test paper.
Hirsch, I., Reddick, J. M.
core +1 more source
A Rapid, Simple, Inexpensive, and Mobile Colorimetric Assay COVID-19-LAMP for Mass On-Site Screening of COVID-19 [PDF]
Franklin Wang‐Ngai Chow +26 more
openalex +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Potential between external monopole and antimonopole in SU(2) lattice glu odynamics
We present the results of a study of the free energy of a monopole pair in pure SU(2) theory at finite temperature, both below and above the deconfinement tran sition. We find a Yukawa potential between monopoles in both phases.
't Hooft +18 more
core +1 more source
The role of histone modifications in transcription regulation upon DNA damage
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley +1 more source
The performance of the Mini-Cog in a sample of low educational level elderly
Objectives: To study the criterion validity of the Mini-Cog in low educational level elderly. Design: Cross-sectional and validation design. Setting: Policlínica Piquet Carneiro, an outpatient unit of Rio de Janeiro State University Hospital, in Brazil.
Sergio Telles Ribeiro Filho +1 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Generalization of radiative jet energy loss to non-zero magnetic mass
Reliable predictions for jet quenching in ultra-relativistic heavy ion collisions require accurate computation of radiative energy loss. With this goal, an energy loss formalism in a realistic finite size dynamical QCD medium was recently developed ...
Armesto +40 more
core +1 more source

