Results 161 to 170 of about 1,793,744 (301)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Opinions, practice patterns, and perceived barriers to lung cancer screening among attending and resident primary care physicians

Risk Management and Healthcare Policy, 2018
Louise M Henderson,1 Laura M Jones,1 Mary W Marsh,1 Alison T Brenner,2,3 Adam O Goldstein,4 Thad S Benefield,1 Mikael Anne Greenwood-Hickman,5 Paul L Molina,1 M Patricia Rivera,2 Daniel S Reuland2,3 1Department of Radiology, The University of North ...
Henderson LM, Jones LM, Marsh MW, Brenner AT, Goldstein AO, Benefield TS, Greenwood-Hickman MA, Molina PL, Rivera MP, Reuland DS   +9 more
doaj  

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

A Pilot Project of Systematic Tuberculosis Screening in the Elderly in a South Korean Province

Tuberculosis and Respiratory Diseases, 2019
Background Tuberculosis (TB) is a major infectious disease in South Korea causing substantial disease burden, particularly in the elderly. This study aimed to identify the case detection rate of mobile TB screening for the elderly conducted in the ...
Hyunwoo Kim, M.P.H., Hee-Jin Kim, M.D., M.P.H., Kyung-Hyun Oh, M.D., M.P.H., Hwan-Wook Oh, B.P.H., Hongjo Choi, M.D., Ph.D.   +4 more
doaj  

Modeling Low Muscle Mass Screening in Hemodialysis Patients.

Nephron, 2023
Senzaki D, Yoshioka N, Nagakawa O, Inayama E, Nakagawa T, Takayama H, Endo T, Nakajima F, Fukui M, Kijima Y, Oyama Y, Kudo R, Toyama T, Yamada Y, Tsurusaki K, Aoyama N, Matsumura T, Yamahara H, Miyasato K, Kitamura T, Ikenoue T.   +20 more
europepmc   +1 more source

Mass screening is a key component to fight against SARS-CoV-2 and return to normalcy. [PDF]

Med Rev (2021), 2022
Feng Z, Zhang Y, Pan Y, Zhang D, Zhang L, Wang Q.   +5 more
europepmc   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

A deep learning model for mass screening of COVID-19. [PDF]

Int J Imaging Syst Technol, 2021
Dhaka VS, Rani G, Oza MG, Sharma T, Misra A.   +4 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

A cost-benefit algorithm for rapid diagnosis of tuberculosis and rifampicin resistance detection during mass screening campaigns. [PDF]

BMC Infect Dis, 2022
Donkeng-Donfack VF, Tchatchueng-Mbougua JB, Abanda NN, Ongboulal SM, Djieugoue YJ, Kamdem Simo Y, Mekemnang Tchoupa M, Bekang Angui F, Kuate Kuate A, Mbassa V, Mvondo Abeng Belinga E, Eyangoh S.   +11 more
europepmc   +1 more source