Results 11 to 20 of about 1,500,628 (349)
Multi-omic analyses of triptan-treated migraine attacks gives insight into molecular mechanisms
Scientific Reports, 2023 Migraine is a common, polygenic disorder that is characterized by moderate to severe headache attacks. Migraine attacks are commonly treated with triptans, i.e. serotonin receptor agonists.
Lisette J. A. Kogelman +10 more
doaj +1 more source
Advances in high‐throughput mass spectrometry in drug discovery
EMBO Molecular Medicine, 2023 High‐throughput (HT) screening drug discovery, during which thousands or millions of compounds are screened, remains the key methodology for identifying active chemical matter in early drug discovery pipelines.
Maria Emilia Dueñas +5 more
doaj +1 more source
INAPPROPRIATE REQUESTS FOR TUMOR MARKERS IN PATIENTS AGED 50 YEARS AND OLDER: LESSONS NOT LEARNED [PDF]
Geriatrics, Gerontology and Aging, 2021 OBJECTIVE: To investigate, within a private health insurance, the ordering frequency and the costs related to inappropriate tumor markers test orders. METHODS: This study analyzed data regarding tumor markers requests within a private health insurance ...
Valter Paz Nascimento-Júnior +1 more
doaj +1 more source
BMC Research Notes, 2022 Objective We developed an assay to measure the concentration of 25 hydroxyvitamin D2 and D3 in protein extracts derived from stored neonatal dried blood spots.
Sanne Grundvad Boelt +5 more
doaj +1 more source
Sharing With Patients the Uncertainties Regarding the Management of Dyspepsia
Frontiers in Medicine, 2021 Background: The management of patients with dyspepsia is uncertain. Some authors advocate endoscopy for all; others restrict endoscopy only to patients at high risk of gastric cancer, namely to those above an age threshold, or with a family history ...
Jochanan Benbassat
doaj +1 more source
Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study
Scientific Reports, 2021 Spermine oxidase (SMOX) catalyzes the oxidation of spermine to spermidine. Observational studies have reported SMOX as a source of reactive oxygen species associated with cancer, implying that inhibition of SMOX could be a target for chemoprevention ...
João Fadista +17 more
doaj +1 more source
Laboratory management for large‐scale population screening for SARS‐CoV‐2
Immunity, Inflammation and Disease, 2022 Introduction The aim of this study was to investigate the improvements in laboratory testing procedures and the quality and safety management for large‐scale population screening for severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2).
Xiuzhi Duan +11 more
doaj +1 more source
Magnetic confinement and screening masses [PDF]
Physics Letters B, 1995 Confined and deconfined phases are defined through nonperturbative correlators and nonperturbative background perturbation theory is used to compute the critical temperature $T_c$ and spatial string tension. Taking evolution along one of the spatial axes the set of Hamiltonians $H(n_1,n_2)$ with different Matsubara frequencies is obtained.
Elena Gubankova, Yu. A. Simonov
openaire +3 more sources
Screening masses in gluonic plasma [PDF]
Physical Review D, 2012 Accepted in ...
Purnendu Chakraborty +2 more
openaire +3 more sources
Bioaffinity Mass Spectrometry Screening [PDF]
SLAS Discovery, 2016 Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI-FTICR-MS or ESI-FTMS) was used to screen 192 natural product extracts and a 659-member natural product-based fragment library for bindings to a potential malaria drug target, Plasmodium falciparum Rab11a (PfRab11a, PF13_0119).
Yang, Ben +9 more
openaire +4 more sources