Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study
Spermine oxidase (SMOX) catalyzes the oxidation of spermine to spermidine. Observational studies have reported SMOX as a source of reactive oxygen species associated with cancer, implying that inhibition of SMOX could be a target for chemoprevention ...
João Fadista +17 more
doaj +1 more source
Comprehensive Screening for COVID-19 at St. Petersburg Oncology Centre
Background. Clinical reports on the coronavirus disease 2019 (COVID-19) suggest its higher incidence and worse outcomes in cancer patients. Considering a rapid pace of the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) pandemic ...
N. M. Volkov +12 more
doaj +1 more source
Pubo-Femoral Distances Measured Reliably by Midwives in Hip Dysplasia Ultrasound
The pubo-femoral distance (PFD) has been suggested as an ultrasound screening tool for developmental dysplasia of the hip (DDH). The aim of this study was to examine if midwives undergoing minimal training could reliably perform pediatric hip ultrasound ...
Hans-Christen Husum +6 more
doaj +1 more source
Association of the FRAIL Scale with Geriatric Syndromes and Health-Related Outcomes in Korean Older Adults [PDF]
Background Owing to the growing older population, appropriate tools are needed for frailty screening in community-dwelling older people. We investigated the association between geriatric conditions and health-related outcomes using the five-item Fatigue,
Heayon Lee +5 more
doaj +1 more source
Detecting Early Pancreatic Cancer: Current Problems and Future Prospects
The number of patients with pancreatic cancer (PC) is currently increasing in both Korea and Japan. The 5-year survival rate of patients with PC 13.0%; however, resection with minimal invasion (tumor size: ≤10 mm) increases the 5-year survival rate to 80%
Hiroyuki Matsubayashi +4 more
doaj +1 more source
Bioaffinity Mass Spectrometry Screening [PDF]
Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI-FTICR-MS or ESI-FTMS) was used to screen 192 natural product extracts and a 659-member natural product-based fragment library for bindings to a potential malaria drug target, Plasmodium falciparum Rab11a (PfRab11a, PF13_0119).
Yang, Ben +9 more
openaire +3 more sources
Screening Masses Towards Chiral Limit [PDF]
A possible effective restoration of the anomalous $U_A(1)$ symmetry would have a non-trivial effect on the global phase diagram of QCD. In this work we investigate the effective restoration of the $U_A(1)$ through the calculation of scalar and pseudo-scalar screening masses and corresponding susceptibilities, for physical and lower than physical pion ...
Dentinger, Simon +2 more
openaire +3 more sources
Development and Validation of a Deep Learning Based Diabetes Prediction System Using a Nationwide Population-Based Cohort [PDF]
Background Previously developed prediction models for type 2 diabetes mellitus (T2DM) have limited performance. We developed a deep learning (DL) based model using a cohort representative of the Korean population.
Sang Youl Rhee +5 more
doaj +1 more source
Background: KwaZulu–Natal, South Africa has one of the highest HIV prevalence rates globally. Persons <35 years and men have lower rates of HIV testing.
Nsika Sithole +17 more
doaj +1 more source
INAPPROPRIATE REQUESTS FOR TUMOR MARKERS IN PATIENTS AGED 50 YEARS AND OLDER: LESSONS NOT LEARNED [PDF]
OBJECTIVE: To investigate, within a private health insurance, the ordering frequency and the costs related to inappropriate tumor markers test orders. METHODS: This study analyzed data regarding tumor markers requests within a private health insurance ...
Valter Paz Nascimento-Júnior +1 more
doaj +1 more source

