Results 21 to 30 of about 5,393,319 (311)

Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study

Scientific Reports, 2021
Spermine oxidase (SMOX) catalyzes the oxidation of spermine to spermidine. Observational studies have reported SMOX as a source of reactive oxygen species associated with cancer, implying that inhibition of SMOX could be a target for chemoprevention ...
João Fadista, Victor Yakimov, Urmo Võsa, Christine S. Hansen, Silva Kasela, Line Skotte, Frank Geller, Julie Courraud, Tõnu Esko, Viktorija Kukuškina, Alfonso Buil, Mads Melbye, Thomas M. Werge, David M. Hougaard, Lili Milani, Jonas Bybjerg-Grauholm, Arieh S. Cohen, Bjarke Feenstra   +17 more
doaj   +1 more source

Final follow-up of the Multicentre Aneurysm Screening Study (MASS) randomized trial of abdominal aortic aneurysm screening [PDF]

, 2012
Background: The long-term effects of abdominal aortic aneurysm (AAA) screening were investigated in extended follow-up from the UK Multicentre Aneurysm Screening Study (MASS) randomized trial.
Gao, L, Thompson, SG, Ashton, HA, Scott, RAP, Buxton, MJ   +4 more
core   +2 more sources

Cost-effectiveness of the National Health Service Abdominal Aortic Aneurysm Screening Programme in England. [PDF]

, 2014
BACKGROUND: Implementation of the National Health Service abdominal aortic aneurysm (AAA) screening programme (NAAASP) for men aged 65 years began in England in 2009.
Thompson, SG, Glover, MJ, Kim, LG, Buxton, MJ, Sweeting, MJ, Buxton, M. J., Kim, L. G., Glover, M. J., Sweeting, M. J., Thompson, S. G.   +9 more
core   +1 more source

Multiplexed screening of thousands of natural products for protein-ligand binding in native mass spectrometry [PDF]

, 2021
The structural diversity of natural products offers unique opportunities for drug discovery, but challenges associated with their isolation and screening can hinder the identification of drug-like molecules from complex natural product extracts.
Dominic, Glover, Sherrie , Liu, William, Donald, Giang, Nguyen, Sarah, Hancock, Jack, Bennett, Daniel, Winter   +6 more
core   +2 more sources

Anticipated regret to increase uptake of colorectal cancer screening (ARTICS):a randomised controlled trial [PDF]

, 2015
Screening is important for early detection of colorectal cancer. Our aim was to determine whether a simple anticipated regret (AR) intervention could increase uptake of colorectal cancer screening. A randomised controlled trial of a simple, questionnaire-
Brownlee, Linda A., Steele, Robert J. C., O'Carroll, Ronan E., Steele, Robert, Chambers, Julie A., Chambers, Julie, Brownlee, Linda, Libby, Gillian, O'Carroll, Ronan   +8 more
core   +1 more source

A Simple and Rapid Test-card Method to Detect Hepatitis B Surface Antigen and Antibody: Potential Application in Young Children and Infants

Pediatrics and Neonatology, 2016
Hepatitis B surface antigen (HBsAg) and hepatitis B surface antibody (anti-HBs) were conventionally determined by enzyme immunoassays. We aimed to apply a rapid, simple, and accurate method to detect HBsAg and its antibody.
Fu-Yu Wu, Yu-Wun Liao, Jia-Feng Wu, Huey-Ling Chen, Hong-Yuan Hsu, Mei-Hwei Chang, Yen-Hsuan Ni   +6 more
doaj   +1 more source

CT Examinations for COVID-19: A Systematic Review of Protocols, Radiation Dose, and Numbers Needed to Diagnose and Predict

대한영상의학회지, 2021
Purpose Although chest CT has been discussed as a first-line test for coronavirus disease 2019 (COVID-19), little research has explored the implications of CT exposure in the population.
Jong Hyuk Lee, Hyunsook Hong, Hyungjin Kim, Chang Hyun Lee, Jin Mo Goo, Soon Ho Yoon   +5 more
doaj   +1 more source

Metabolite-protein interactions: Native mass spectrometry and collision induced affinity selection mass spectrometry in natural product screening

, 2022
Understanding molecular level interactions between the metabolome and proteome, two of the most important classes of molecules in biology, will generate deeper insight into the function of metabolites (natural products) which have a central role in ...
Liu, Miaomiao, Quinn, Ronald J, Gu, Yushu   +2 more
core   +1 more source

Inter-arm blood pressure difference and cardiovascular risk estimation in primary care: a pilot study

BJGP Open, 2022
Background: Systolic inter-arm differences (IAD) in blood pressure (BP) contribute independently to cardiovascular risk estimates. This can be used to refine predicted risk and guide personalised interventions.
Sinead T J McDonagh, Ben Norris, A Jayne Fordham, Maria R Greenwood, Suzanne H Richards, John L Campbell, Christopher E Clark   +6 more
doaj   +1 more source

Recommendations for a colorectal cancer screening programme in Ireland [PDF]

, 2008
In April 2007, the National Cancer Screening Service Board established an expert advisory group to study the medical and scientific evidence concerning screening for colorectal cancer and to make recommendations to the Board about the potential benefits ...
National Cancer Screening Service
core   +1 more source