Results 11 to 20 of about 943,382 (267)

Genetic regulation of spermine oxidase activity and cancer risk: a Mendelian randomization study

Scientific Reports, 2021
Spermine oxidase (SMOX) catalyzes the oxidation of spermine to spermidine. Observational studies have reported SMOX as a source of reactive oxygen species associated with cancer, implying that inhibition of SMOX could be a target for chemoprevention ...
João Fadista, Victor Yakimov, Urmo Võsa, Christine S. Hansen, Silva Kasela, Line Skotte, Frank Geller, Julie Courraud, Tõnu Esko, Viktorija Kukuškina, Alfonso Buil, Mads Melbye, Thomas M. Werge, David M. Hougaard, Lili Milani, Jonas Bybjerg-Grauholm, Arieh S. Cohen, Bjarke Feenstra   +17 more
doaj   +1 more source

Comprehensive Screening for COVID-19 at St. Petersburg Oncology Centre

Креативная хирургия и онкология, 2021
Background. Clinical reports on the coronavirus disease 2019 (COVID-19) suggest its higher incidence and worse outcomes in cancer patients. Considering a rapid pace of the severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) pandemic ...
N. M. Volkov, M. S. Lebedeva, V. V. Egorenkov, F. V. Moiseenko, N. Kh. Abduloeva, A. A. Bogdanov, I. N. Terterov, V. V. Chernobrivceva, N. E. Valeeva, E. B. Myasnikova, A. S. Navatskaya, A. A. Bogdanov, V. M. Moiseyenko   +12 more
doaj   +1 more source

Bioaffinity Mass Spectrometry Screening [PDF]

SLAS Discovery, 2016
Electrospray ionization Fourier transform ion cyclotron resonance mass spectrometry (ESI-FTICR-MS or ESI-FTMS) was used to screen 192 natural product extracts and a 659-member natural product-based fragment library for bindings to a potential malaria drug target, Plasmodium falciparum Rab11a (PfRab11a, PF13_0119).
Yang, Ben, Feng, Yun Jiang, Vu, Hoan, McCormick, Brendan, Rowley, Jessica, Pedro, Liliana, Crowther, Gregory J., Van Voorhis, Wesley C., Forster, Paul I., Quinn, Ronald J.   +9 more
openaire   +5 more sources

Pubo-Femoral Distances Measured Reliably by Midwives in Hip Dysplasia Ultrasound

Children, 2022
The pubo-femoral distance (PFD) has been suggested as an ultrasound screening tool for developmental dysplasia of the hip (DDH). The aim of this study was to examine if midwives undergoing minimal training could reliably perform pediatric hip ultrasound ...
Hans-Christen Husum, Michel Bach Hellfritzsch, Rikke Damkjær Maimburg, Mads Henriksen, Natallia Lapitskaya, Bjarne Møller-Madsen, Ole Rahbek   +6 more
doaj   +1 more source

Association of the FRAIL Scale with Geriatric Syndromes and Health-Related Outcomes in Korean Older Adults [PDF]

Annals of Geriatric Medicine and Research, 2021
Background Owing to the growing older population, appropriate tools are needed for frailty screening in community-dwelling older people. We investigated the association between geriatric conditions and health-related outcomes using the five-item Fatigue,
Heayon Lee, Junyong Chong, Hee-Won Jung, Ji Yeon Baek, Eunju Lee, Il-Young Jang   +5 more
doaj   +1 more source

Detecting Early Pancreatic Cancer: Current Problems and Future Prospects

Gut and Liver, 2020
The number of patients with pancreatic cancer (PC) is currently increasing in both Korea and Japan. The 5-year survival rate of patients with PC 13.0%; however, resection with minimal invasion (tumor size: ≤10 mm) increases the 5-year survival rate to 80%
Hiroyuki Matsubayashi, Hirotoshi Ishiwatari, Keiko Sasaki, Katsuhiko Uesaka, Hiroyuki Ono   +4 more
doaj   +1 more source

Development and Validation of a Deep Learning Based Diabetes Prediction System Using a Nationwide Population-Based Cohort [PDF]

Diabetes & Metabolism Journal, 2021
Background Previously developed prediction models for type 2 diabetes mellitus (T2DM) have limited performance. We developed a deep learning (DL) based model using a cohort representative of the Korean population.
Sang Youl Rhee, Ji Min Sung, Sunhee Kim, In-Jeong Cho, Sang-Eun Lee, Hyuk-Jae Chang   +5 more
doaj   +1 more source

Implementation of HIV Self-Testing to Reach Men in Rural uMkhanyakude, KwaZulu-Natal, South Africa. a DO-ART Trial Sub Study

Frontiers in Public Health, 2021
Background: KwaZulu–Natal, South Africa has one of the highest HIV prevalence rates globally. Persons <35 years and men have lower rates of HIV testing.
Nsika Sithole, Maryam Shahmanesh, Maryam Shahmanesh, Olivier Koole, Olivier Koole, Meighan Krows, Torin Schaafsma, Mark J. Siedner, Mark J. Siedner, Mark J. Siedner, Connie Celum, Connie Celum, Connie Celum, Ruanne V. Barnabas, Ruanne V. Barnabas, Ruanne V. Barnabas, Adrienne E. Shapiro, Adrienne E. Shapiro   +17 more
doaj   +1 more source

Use of the prostate‐specific antigen (PSA) test in the United States for men age ≥65, 1999–2015: Implications for practice interventions

Cancer Reports, 2021
Background Various professional organizations have issued recommendations on use of the PSA test to screen for prostate cancer in different age groups.
Shahram Shahangian, Lin Fan, Krishna P. Sharma, David A. Siegel   +3 more
doaj   +1 more source

Implementation of the compulsory universal testing scheme in Hong Kong: Mathematical simulations of a household-based pooling approach

Frontiers in Public Health, 2022
This study aims to propose a pooling approach to simulate the compulsory universal RT-PCR test in Hong Kong and explore the feasibility of implementing the pooling method on a household basis.
Kei Shing Ng, Jeffrey Man Hin Hon, Jeffrey Man Hin Hon, Stephen Chau Chun Chong, Howard Ho Kan Cheung, Jeffrey Chan, Simon Ching Lam, Benny Yiu Chung Hon, Benny Yiu Chung Hon   +8 more
doaj   +1 more source