Results 61 to 70 of about 887,132 (304)

Metabolite Dysregulation by Pranlukast in Mycobacterium tuberculosis

Molecules, 2022
Mycobacterium tuberculosis has been infecting millions of people worldwide over the years, causing tuberculosis. Drugs targeting distinct cellular mechanisms including synthesis of the cell wall, lipids, proteins, and nucleic acids in Mtb are currently ...
Soujanya D. Yelamanchi, Sumaithangi Thattai Arun Kumar, Archita Mishra, Thottethodi Subrahmanya Keshava Prasad, Avadhesha Surolia   +4 more
doaj   +1 more source

Orifice gross leak tester Patent [PDF]

, 1971
Test chambers with orifice and helium mass spectrometer for detecting leak rate of encapsulated semiconductor ...
Altshuler, T. L.
core   +1 more source

Quantifying precision and accuracy of measurements of dissolved inorganic carbon stable isotopic composition using continuous-flow isotope-ratio mass spectrometry [PDF]

, 2014
RATIONALE: We describe an analytical procedure that allows sample collection and measurement of carbon isotopic composition (δ13CV-PDB value) and dissolved inorganic carbon concentration, [DIC], in aqueous samples without further manipulation post field
Altman, AMCTB, Analytical Methods Committee, AMCTB, Analytical Methods Committee, Assayag, Atekwana, Barth, Bass, Bass, Bouillon, Brandes, Capasso, Cole, Finlay, Finlay, Geldern, Jones, Klein Gebbinck, Maberly, McCrea, Neter, Polsenaere, Salata, Soulsby, Spötl, St-Jean, Taipale, Torn, Torres, Waldron, Yang   +29 more
core   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Clinical laboratory use of liquid chromatography mass spectrometry

Türk Biyokimya Dergisi, 2022
Mass spectrometric methods, which transition from chemistry laboratories to clinical laboratories in the basic field, are frequently used in areas such as metabolic analysis, endocrinology, drug research, protein studies and toxicology.
Unlu Ali, Abusoglu Sedat
doaj   +1 more source

Automated mass spectrometer/analysis system: A concept [PDF]

, 1975
System performs rapid multiple analyses of entire compound classes or individual compounds on small amounts of sample and reagent. Method will allow screening of large populations for metabolic disorders and establishment of effective-but-safe levels of ...
Boettger, H. G., Dreyer, W. J., Giffin, C. E., Kuppermann, A.   +3 more
core   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

The Peregrine Ion Trap Mass Spectrometer (PITMS): Results from a CLPS-delivered Mass Spectrometer

The Planetary Science Journal
The Peregrine Ion Trap Mass Spectrometer (PITMS) was a mass spectrometer designed to measure lunar gases. PITMS flew on the first flight of Astrobotic’s Peregrine lander via the Commercial Lunar Payload Services (CLPS) program in 2024 January.
Barbara A. Cohen, Simeon J. Barber, Aleksandra J. Gawronska, Feargus A. J. Abernethy, Natalie M. Curran, Phillip A. Driggers, William M. Farrell, David J. Heather, Christopher Howe, Peter F. Landsberg, Veneranda López-Días, Andrew D. Morse, Thomas Morse, Michael J. Poston, Parvathy Prem, Roland Trautner, Orenthal J. Tucker, Tristram J. Warren, Stefano Boccelli   +18 more
doaj   +1 more source

Application of a quasi-open ion source for neutral particle density measurements in the thermosphere [PDF]

, 1966
Open ion source mass spectrometer used with omegatron mass spectrometer to measure atmospheric gas density and composition in thermosphere probe ...
Kreick, J. R., Niemann, H. B.
core   +1 more source

Hands‐on protocol for preparing water‐soluble fractions from agri‐food samples for NMR‐based metabolomics analysis

FEBS Open Bio, EarlyView.
This research protocol outlines a workflow for nuclear magnetic resonance (NMR)‐based metabolomics in the agri‐food sector. Using two case studies—strawberry leaves (solid matrix) and wine (liquid matrix)—it details the procedures for sample preparation, data acquisition, and processing.
Andrea Fernández‐Veloso, Jaime Hiniesta‐Valero, Alejandra Guerra‐Castellano, Miguel A. De la Rosa, Irene Díaz‐Moreno   +4 more
wiley   +1 more source