Results 101 to 110 of about 5,492,223 (387)

Detection strategies for bioassays based on liquid chromatography, fluorescence spectroscopy and mass spectrometry [PDF]

, 2005
New detection strategies for bioassays based on liquid chromatography,\ud fluorescence spectroscopy and mass spectrometry were developed and are\ud presented within this ...
Hempen, Christel Maria
core   +1 more source

Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?

Molecular Oncology, EarlyView.
Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley   +1 more source

Detection of metastable electronic states by Penning trap mass spectrometry

, 2020
State-of-the-art optical clocks achieve fractional precisions of $10^{-18}$ and below using ensembles of atoms in optical lattices or individual ions in radio-frequency traps.
Bekker, Hendrik, Blaum, Klaus, Braß, Martin, Cakir, Halil, Door, Menno, Eliseev, Ssergey, Filianin, Pavel, Harman, Zoltan, Haverkort, Maurits W., Huang, Wen Jia, Indelicato, Paul, Keitel, Christoph Helmut, Kromer, Kathrin, König, Charlotte Maria, López-Urrutia, José R. Crespo, Müller, Marius, Novikov, Yuri N., Rischka, Alexander, Schweiger, Christoph, Schüssler, Rima Xenia, Sturm, Sven, Ulmer, Stefan   +21 more
core   +2 more sources

Rapid identification of E. coli bacteriophages using mass spectrometry [PDF]

, 2017
Objective: The current increasing interest in the application of mass spectrometry, in particular MALDI-TOF MS, to identification of bacteria and fungi calls for a need to utilise this technology for identification of other infectious agents such as ...
Pantoja Munoz, Leonardo, Ring, Christopher J., Serafim, Vlad, Shah, Ajit J., Shah, H.   +4 more
core   +1 more source

Integrative analysis of multimodal mass spectrometry data in MZmine 3

Nature Biotechnology, 2023
Robin Schmid, S. Heuckeroth, A. Korf, Aleksandr Smirnov, Owen D. Myers, Thomas S. Dyrlund, Roman Bushuiev, Kevin J Murray, Nils Hoffmann, Miaoshan Lu, Abinesh Sarvepalli, Zheng Zhang, Markus Fleischauer, Kai Dührkop, Mark Wesner, Shawn J. Hoogstra, E. Rudt, Olena Mokshyna, Corinna Brungs, Kirill Ponomarov, Lana Mutabdžija, Tito Damiani, C. Pudney, M. Earll, Patrick O. Helmer, Timothy R. Fallon, T. Schulze, Albert Rivas‐Ubach, Aivett Bilbao, H. Richter, Louis-Félix Nothias, Mingxun Wang, M. Orešič, J. Weng, Sebastian Böcker, A. Jeibmann, H. Hayen, U. Karst, P. Dorrestein, D. Petráš, Xiuxia Du, T. Pluskal   +41 more
semanticscholar   +1 more source

A Cyclic Ion Mobility-Mass Spectrometry System.

Analytical Chemistry, 2019
Improvements in the performance and availability of commercial instrumentation have made ion mobility-mass spectrometry (IM-MS) an increasingly popular approach for the structural analysis of ionic species as well as for separation of complex mixtures ...
K. Giles, J. Ujma, J. Wildgoose, Steven Pringle, K. Richardson, D. Langridge, M. Green   +6 more
semanticscholar   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Simultaneous mass spectrometry imaging of multiple neuropeptides in the brain and alterations induced by experimental parkinsonism and L-DOPA therapy

Neurobiology of Disease, 2020
Neuropeptides are important signalling molecules in the brain and alterations in their expression levels have been linked to neurological disorders such as Parkinson's disease. It is challenging to map neuropeptide changes across and within brain regions
Heather Hulme, Elva Fridjonsdottir, Halla Gunnarsdottir, Theodosia Vallianatou, Xiaoqun Zhang, Henrik Wadensten, Reza Shariatgorji, Anna Nilsson, Erwan Bezard, Per Svenningsson, Per E. Andrén   +10 more
doaj  

High-throughput detection of antioxidants in mulberry fruit using correlations between high-resolution mass and activity profiles of chromatographic fractions

Plant Methods, 2017
Background Plant extracts contain a huge variety of pharmacologically active substances. Conventionally, various chromatographic methods must be applied several times to purify functional compounds to measure their functional activity.
Ye Ji Park, Si Hyun Seong, Min Sun Kim, Sang Wan Seo, Mee Ree Kim, Hyun Sik Kim   +5 more
doaj   +1 more source

Mass spectrometry of aerospace materials [PDF]

Mass spectrometry is used for chemical analysis of aerospace materials and contaminants. Years of analytical aerospace experience have resulted in the development of specialized techniques of sampling and analysis which are required in order to optimize ...
Colony, J. A.
core   +1 more source