Results 111 to 120 of about 1,058,705 (300)

Myosin Va: Capturing cAMP for synaptic plasticity

Frontiers in Physiology
The plus-end directed actin-dependent motor protein, myosin Va, is of particular relevance for outward vesicular protein trafficking and for restraining specific cargo vesicles within the actin cortex.
Rüdiger Rudolf, Rüdiger Rudolf, Rüdiger Rudolf   +2 more
doaj   +1 more source

Lattice calculations of the spectroscopy of baryons with broken flavor SU(3) symmetry and 3, 5, or 7 colors

, 2013
Lattice Monte Carlo calculations of baryon spectroscopy in gauge groups SU(N), N=3, 5, 7, are presented. The quenched valence fermions come in three flavors, two degenerate mass ones and a third heavier flavor.
DeGrand, Thomas
core   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

From Sample to Mixed Reality: A Translational 3D MALDI Imaging Platform for Advanced 3D Spatial Omics Analysis of 3D Cell Culture Disease Models

Advanced Science
Human 3D cell cultures, including spheroids and organoids, are essential biological models for translational pharmaceutical and biomedical research. However, their 3D analysis using 2D‐ matrix‐assisted laser desorption/ionization (MALDI) imaging‐based ...
Stefania Alexandra Iakab, Jonas Cordes, Thomas Enzlein, Florian Keller, Kevin Kastner, Theresa Mulholland, Björn Christian Fröhlich, Lars Gruber, James Lucas Cairns, Stefan Schmidt, Mathias Hafner, Richard Schneider, Johannes Betge, Frank Fischer, Julian Reichwald, Rüdiger Rudolf, Carsten Hopf   +16 more
doaj   +1 more source

Assessing the Sensitivity and Efficiency of Laser-Induced Breakdown Spectroscopy (LIBS) for High-Concentration Cadmium Detection in Cocoa Powder

Sensors
Cocoa is a major commodity in the global food industry. Heavy metal contamination, particularly cadmium (Cd), raises significant concerns. This work demonstrates the use of laser-induced breakdown spectroscopy (LIBS) for fast Cd quantification in ...
Juan Molina M., Raquel Pincay, Víctor Santos, José Luis González, María Fernanda Trujillo Guerrero, Diego Díaz Pace, César Costa-Vera   +6 more
doaj   +1 more source

Unraveling the Conformational Preference of Morpholine: Insights from Infrared Resonant Vacuum Ultraviolet Photoionization Mass Spectroscopy. [PDF]

J Phys Chem Lett, 2023
Park SM, Kwon CH.
europepmc   +1 more source

Predictive Ability of Plasma p‐tau217 for β‐Amyloid Status: A Prospective Multicenter Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Plasma tau phosphorylated at threonine 217 (p‐tau217) measured with fully automated platforms has shown high accuracy for Alzheimer's disease (AD) diagnosis, but real‐world multicenter data remain limited. We aimed to validate the diagnostic performance of p‐tau217 for identifying AD pathology in a real‐world multicenter cohort ...
Miquel Massons, Nuria Guillen, Jordi Sarto, Neus Falgàs, Sergi Borrego‐Écija, Diana Esteller‐Gauxax, Magda Castellví, Adrià Tort‐Merino, Agnès Pérez‐Millan, Anna Antonell, Josep M. Augè Fradera, Gerard Piñol, Iolanda Riba, Anna Carnes‐Vendrell, Marta Cullell, Maria Teresa Osuna, Lorena Bajo, Teresa Romero, Eva Bonjoch, Joan Bello, Susana Fernández, Marta Balagué, Isabel Gómez‐Ruiz, Anuncia Boltes, Claustre Pont, Raquel Cuevas, Sara Carrillo, Laura Iglesias, Teresa Maria Casadevall Codina, Lorena Grau Guinea, Fernando Jose Espada, Raquel Sánchez‐Valle, Mircea Balasa, Albert Lladó   +33 more
wiley   +1 more source

Potential glioblastoma biomarkers identified by mass spectroscopy and iTRAQ labeling. [PDF]

Genes Dis, 2023
Feng R, Chen M, Luo G, Chen Y, Wang J, Xu J, Xu M, Zhong P, Wen T.   +8 more
europepmc   +1 more source

Metabolomic reprogramming of the tumor microenvironment by dual arginase inhibitor OATD-02 boosts anticancer immunity

Scientific Reports
Metabolic reprogramming within the tumor microenvironment (TME) plays a central role in cancer progression and immune evasion, with L-arginine metabolism emerging as a key regulatory axis.
Marcin Mikołaj Grzybowski, Yasemin Uçal, Angelika Muchowicz, Tomasz Rejczak, Agnieszka Kikulska, Katarzyna Maria Głuchowska, Małgorzata Szostakowska-Rodzoś, Agnieszka Zagożdżon, Tobias Bausbacher, Agnieszka Tkaczyk, Magdalena Kulma, Paulina Pomper, Michał Mlącki, Adam Konrad Jagielski, Roman Błaszczyk, Carsten Hopf, Zbigniew Zasłona   +16 more
doaj   +1 more source

Multi-omics combined with MALDI mass spectroscopy imaging reveals the mechanisms of biosynthesis of characteristic compounds in Tetrastigma hemsleyanum Diels et Gilg. [PDF]

Front Plant Sci, 2023
Lin Y, Jiang X, Zhu S, Dun J, Pu J, Liang W.   +5 more
europepmc   +1 more source