Results 61 to 70 of about 2,357,818 (294)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Top-quark mass from the diphoton mass spectrum

open access: yesEuropean Physical Journal C: Particles and Fields, 2017
We calculate the $$gg\rightarrow \gamma \gamma $$ g g → γ γ amplitude by including the $$t\bar{t}$$ t t ¯ bound-state effects near their mass threshold.
Sayaka Kawabata, Hiroshi Yokoya
doaj   +1 more source

Soft breaking of $L_\mu-L_\tau$ symmetry: Light neutrino spectrum and Leptogenesis

open access: yes, 2006
Continuous $U(1)_{L_\mu-L_\tau}$ symmetry can generate quasi degenerate mass spectrum for both left handed light and right handed heavy Majorana neutrinos assuming that the symmetry preserving non zero parameters are nearly same. There is an accidental $\
B. Pontecorvo   +13 more
core   +2 more sources

Microscopic twisted-mass Dirac spectrum

open access: yesPhysical Review D, 2012
The microscopic spectral density for lattice QCD with two flavors and maximally twisted mass is computed. The results are given for fixed index of the Dirac operator and include the leading order $a^2$ corrections to the chiral Lagrangian due to the discretization errors. The computation is carried out within the framework of Wilson chiral perturbation
Splittorff, Kim, Verbaarschot, J.J.M.
openaire   +4 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Enhancing MALDI time-of-flight mass spectrometer performance through spectrum averaging. [PDF]

open access: yesPLoS ONE, 2015
Matrix-assisted laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometers are simple and robust mass spectrometers used for analysis of biologically relevant molecules in diverse fields including pathogen identification, imaging mass ...
Morgan Mitchell   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Overview of AI-Based Scent Creation

open access: yesSensors
Although odor classification and odor quantification by e-nose have been studied for a long time, the next stage is to express a detected scent using language.
Takamichi Nakamoto, Manuel Aleixandre
doaj   +1 more source

Crowdsourcing Public Perceptions of Plastic Surgeons: Is There a Gender Bias?

open access: yesPlastic and Reconstructive Surgery, Global Open, 2018
Background:. Implicit gender bias may result in lower wages for women, fewer leadership positions, and lower perceived competence. Understanding public and patient gender preferences for plastic surgeons may enable opportunities to address public ...
Alexandra Bucknor, MBBS, MSc, MRCS   +8 more
doaj   +1 more source

T-duality in M-theory and supermembranes [PDF]

open access: yes, 1997
The (q_1,q_2) SL(2,Z) string bound states of type IIB superstring theory admit two inequivalent (T-dual) representations in eleven dimensions in terms of a fundamental 2-brane.
Aharony   +24 more
core   +2 more sources

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