Results 81 to 90 of about 2,357,818 (294)
Multi-Higgs Mass Spectrum in Gauge-Higgs Unification
, 2008 We study an SU(2) supersymmetric gauge model in a framework of gauge-Higgs unification. Multi-Higgs spectrum appears in the model at low energy. We develop a useful perturbative approximation scheme for evaluating effective potential to study the multi ...
Kazunori Takenaga +6 more
core +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
BPS mass spectrum from D-brane action
, 1996 We derive the BPS mass formulae of the Dirichlet branes from the Born-Infeld type action. BPS saturation is realized when the brane has the minimal volume while keeping the appropriate winding numbers. We apply the idea to two cases, type IIA superstring
Aspinwall +47 more
core +1 more source
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
Mass Spectrum and Higgs Profile in BLSSM
, 2016 We investigate the predictions on the mass spectrum and Higgs boson decays in the supersymmetric standard model extended by U(1)_B-L symmetry (BLSSM). The model requires two singlet Higgs fields, which are responsible for the radiative breaking of U(1)_B-
Ozdal, Ozer, Un, Cem Salih
core +1 more source
FEBS Open Bio, EarlyView.A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
On the primordial black hole mass function for broad spectra
Physics Letters B, 2020 We elaborate on the mass function of primordial black holes in the case in which the power spectrum of the curvature perturbation is broad. For the case of a broad and flat spectrum, we argue that such a mass function is peaked at the smallest primordial
V. De Luca, G. Franciolini, A. Riotto
doaj +1 more source
Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains
FEBS Open Bio, EarlyView.The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley +1 more source