Results 81 to 90 of about 5,102,595 (240)

Smaller is better: nanobodies meet NMR

open access: yesFEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source

Selector for the Spectrum Art Award 2018. Spectrum, London.

open access: yes, 2018
Billingham was invited to be part of the selection panel for the first Spectrum Award in 2018 alongside Mark Wallinger, Charming Baker, Professor Simon Baron-Cohen, Sacha Craddock and Mary Simpson.
Billingham, R.
core   +4 more sources

A spectral differential characterization of low-mass companions

open access: yesEPJ Web of Conferences, 2013
We present a new approach with which the dynamical mass of low-mass companions around cool stars can be found. In order to discover companions to late-type stars the stellar spectrum is removed.
Lyubchik Y.   +4 more
doaj   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

open access: yesFEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Mass spectrum of gapped, non-confining theories with multi-scale dynamics

open access: yesJournal of High Energy Physics, 2019
We study the mass spectrum of spin-0 and spin-2 composite states in a one-parameter family of three-dimensional field theories by making use of their dual descriptions in terms of supergravity.
Daniel Elander   +4 more
doaj   +1 more source

A mass spectrum-oriented computational method for ion mobility-resolved untargeted metabolomics. [PDF]

open access: yesNat Commun, 2023
Luo M   +6 more
europepmc   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

open access: yesMolecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla   +9 more
wiley   +1 more source

When self-similarity meets mass spectrum and anisotropy

open access: yesAstronomy & Astrophysics
Context. Self-similar evolution is widely used in the theory of collisional stellar dynamics, but its applicability to systems with multiple stellar masses is not well established. Aims.
Pavlík Václav
doaj   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

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