Results 111 to 120 of about 944,227 (303)
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski +12 more
wiley +1 more source
Investigation of heat transfer augmentation through use of internally finned and roughened tubes : final summary report [PDF]
This report summarizes a three-year program concerned with obtaining basic design information for tubes having a random roughness on the inside wall (RID) and tubing having continuous internal fins (Forge Fin).
Brown, G. S. +4 more
core
Mass And Heat Transfer By High Rayleigh Number Convection In A Porous Medium Heated From Below
This paper outlines a combined theoretical and numerical study of the mass transfer effected by high Rayleigh number Bénard convection in a two-dimensional saturated porous layer heated from below.
Trevisan O.V. +3 more
core +1 more source
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
The fully developed laminar flow and heat transfer for ducts with rectangular and trapezoidal cross section in fuel cells have been numerically simulated with one porous wall with a uniform mass injection or suction, while the other three walls being ...
Bengt Sundén +5 more
core +1 more source
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller +10 more
wiley +1 more source
An analytical solution for mass diffusion in a spherical microporous particle experienced with a small step change of gaseous phase adsorbate concentration is obtained.
Ni, C.C., San, J.Y.
core +1 more source
Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
The forecast of formation of the ferrous metals chips in the Republic of Belarus is carried out.
V. I. Timoshpolski +3 more
doaj
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source

