Results 101 to 110 of about 944,227 (303)

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Hydrodynamic and mass transfer in inertial gas–liquid flow regimes through straight and meandering millimetric square channels [PDF]

open access: yes, 2011
Heat-exchanger reactors are an important part of process intensification technology. For plate geometries, one solution for intensifying transfer and increasing residence times is to construct two-dimensional meandering channels.
Michel Cabassud   +7 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Investigation on heat and mass transfer in hygroscopic random charged fiber webs

open access: yes, 2012
Hygroscopic charged fiber webs include a large number of interconnected capillaries formed by randomly distributed pores. The simultaneous heat and mass transfer in hygroscopic charged fiber webs is different from traditional flows in macro-channels ...
Yang, J.   +3 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Recent Progress in Heat and Mass Transfer Modeling for Chemical Vapor Deposition Processes

open access: yes
Chemical vapor deposition (CVD) is a vital process for deposit of thin films of various materials with precise control over the thickness, composition, and properties.
Dmytro Svyetlichnyy, Łukasz Łach
core   +1 more source

Heat and Mass Transfer during Baking: Product Quality aspects [PDF]

open access: yes, 2005
Most food product qualities are developed during heating processes. Therefore the internal heating and mass transfer of water are important aspects in food processing. Heating of food products is mostly induced by convection heating.
Hadiyanto, H., hadiyanto, hady
core  

Influence of chitosan and porosity on heat and mass transfer in chitosan-treated porous fibrous material

open access: yes, 2011
This paper focuses on a theoretical investigation of the coupling mechanism of heat transfer and liquid moisture diffusion in chitosan-treated porous fibrous material.
Yang, J.   +4 more
core   +1 more source

Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization

open access: yesMolecular Oncology, EarlyView.
In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu   +13 more
wiley   +1 more source

NEW MECHANISMS FOR NANOINDENTATION DATA PROCESSING USING ATOMIC FORCE MICROSCOPY METHOD

open access: yesНаука и техника, 2015
Elastic modulus accuracy using atomic force microscopy  depends significantly on processing quality of the experimental data obtained during nanoindentation.  Multiply repeated calibration can lead to conservative value of the calibration factor.
A. A. Mohammed Salem   +3 more
doaj  

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