Results 81 to 90 of about 944,227 (303)

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Isothermal Evaporation Rate of Deposited Liquid Aerosols and the SARS-CoV-2 Coronavirus Survival

Aerosol and Air Quality Research, 2020
It is shown that the evaporation rate of a liquid sample with the height is about several millimeters containing the culture of coronavirus affects its survival on a substrate.
Pavel S. Grinchuk, Katya I. Fisenko, Sergey P. Fisenko, Svetlana M. Danilova-Tretiak   +3 more
doaj   +1 more source

Hydrodynamic and mass transfer efficiency of ceramic foam packing applied to distillation. [PDF]

, 2009
In addition to a high void volume and specific area, solid foams possess other properties (low density, good thermal, mechanical, electrical, and acoustical behaviour) that make them attractive for applications such as heat exchangers and reformers ...
Prevost, Michel, Rouzineau, David, Lévêque, Julien, Meyer, Michel   +3 more
core   +1 more source

Modelling of Coupled Heat and Mass Transfer in a Water-Cooled Falling-Film Absorber Working with an Aqueous Alkaline Nitrate Solution

, 2021
A theoretical model was developed to investigate a falling-film absorber on horizontal tubes with an aqueous alkaline nitrate solution as working fluid. The absorbent, composed of an aqueous solution of nitrates (Li, K, Na) in salt mass percentages of 53%
Mahmoud Bourouis, María E. Álvarez
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Numerical study of heat and mass transfer of ammonia-water in falling film evaporator

, 2011
To investigate the performance of the heat and mass transfer of ammonia water during the process of falling film evaporation in vertical tube evaporator, a mathematical model of evaporation process was developed and solved based on stream function.
Yuanfeng Huang, Ma, Weibin, Weibin Ma, Xianbiao Bu, Huang, Yuanfeng, Bu, Xianbiao   +5 more
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Heat transfer in the vortex zone of a cyclone-bed chamber of furnace unit with fluidized bed

Весці Нацыянальнай акадэміі навук Беларусі: Серыя фізіка-тэхнічных навук, 2019
An experimental investigation of the heat-transfer coefficient to a spherical probe in a cyclone-bed chamber with fluidized bed in the “cold” and “hot” regimes has been carried out.
E. A. Pitsuha, E. K. Buchilko, Yu. S. Teplitskii, D. S. Slizhuk   +3 more
doaj   +1 more source

Surprising effects of combined vapour and liquid mass transfer resistances when condensing a mixture outside tube banks

, 2005
Detailed calculations are carried out for condensation of a binary zeotropic mixture outside a tube bank to investigate combined effects of mass transfer resistances in the liquid and vapour phases.
Karlsson, Tord, Karlsson, Tord,, Vamling, Lennart,, Vamling, Lennart   +3 more
core   +1 more source