Results 41 to 50 of about 819,966 (301)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Investigation of Mass Transfer Coefficient under Jetting Conditions in a Liquid-Liquid Extraction System [PDF]

open access: yesIranian Journal of Chemistry & Chemical Engineering, 2010
In this research mass transfer coefficient under jetting regime in different directions (from dispersed to continuous and continuous to dispersed phase) has been studied using an experimental setup.
Ferial Nosratinia   +3 more
doaj  

Scalability of mass transfer in Taylor flow in capillaries [PDF]

open access: yes, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014)   +2 more
core  

Assessment of a gas-solid vortex reactor for SO2/NOx adsorption from flue gas [PDF]

open access: yes, 2013
The feasibility of performing the SO2/NOx adsorption process in a gas-solid vortex reactor (GSVR) is examined and compared with the more traditional riser technology.
Ashcraft, Robert   +3 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Influence of rotating magnetic field on gas-liquid volumetric mass transfer coefficient

open access: yesChemical and Process Engineering, 2017
The main objective of these experiments was to study the oxygen mass transfer rate through the volumetric mass transfer coefficient (kLa) for an experimental set-up equipped with a rotating magnetic field (RMF) generator and various liquids.
Rakoczy Rafał   +4 more
doaj   +1 more source

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

open access: yesFEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori   +8 more
wiley   +1 more source

Air sparging: Air‐water mass transfer coefficients [PDF]

open access: yesWater Resources Research, 1998
Experiments investigating the mass transfer of several dissolved volatile organic compounds (VOCs) across the air‐water interface were conducted using a single‐air‐ channel air‐sparging system. Three different porous media were used in the study. Air velocities ranged from 0.2 cm s−1 to 2.5 cm s−1.
Washington J. Braida, Say Kee Ong
openaire   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

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