Results 91 to 100 of about 225,767 (306)
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Transverse Instability of Avalanches in Granular Flows down Incline [PDF]
, 2005 Avalanche experiments on an erodible substrate are treated in the framework of ``partial fluidization'' model of dense granular flows. The model identifies a family of propagating soliton-like avalanches with shape and velocity controlled by the ...
Eric Clément +5 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
IMPROVING THE METHOD OF OPEN-PIT LIGNITE DEPOSITS DEVELOPMENT IN UKRAINE [PDF]
, 2018 Subject of the research is open-pit mining concerning a full- field industrial development of a number of lignite deposits; feasibility study has been performed for them as for the efficient environmental friendly processing of coal and associated ...
Adamchuk, A.A. +11 more
core
Cosmic rays in early star-forming galaxies and their effects on the interstellar medium [PDF]
, 2017 Galaxies at high redshifts with strong star formation are sources of high-energy cosmic rays. These cosmic rays interact with the baryon and radiation fields of the galactic environment via photo-pair, photo-pion and proton-proton processes to produce ...
Jacobsen, Idunn B. +3 more
core +2 more sources
RIPK4 function interferes with melanoma cell adhesion and metastasis
Molecular Oncology, EarlyView.RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski +9 more
wiley +1 more source
Geofluids, 2019 Massive greisens are commonly associated with Sn-W mineralization and constitute low-grade high-tonnage deposits. The formation of this type of deposit results from an intense pervasive metasomatic alteration involving a major fluid and mass transfer ...
Gaëtan Launay +5 more
doaj +1 more source
Accelerator Testing of the General Antiparticle Spectrometer, a Novel Approach to Indirect Dark Matter Detection [PDF]
, 2005 We report on recent accelerator testing of a prototype general antiparticle spectrometer (GAPS). GAPS is a novel approach for indirect dark matter searches that exploits the antideuterons produced in neutralino-neutralino annihilations.
Baret B +22 more
core +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Resonant neutrino spin-flavor precession and supernova shock revival [PDF]
, 1996 A new mechanism of supernova shock revival is proposed, which involves resonant spin--flavor precession of neutrinos with a transition magnetic moment in the magnetic field of the supernova.
A. Burrows +52 more
core +4 more sources