Results 71 to 80 of about 227,062 (308)

AAA+ protein unfoldases—the Moirai of the proteome

FEBS Letters, EarlyView.
AAA+ unfoldases are essential molecular motors that power protein degradation and disaggregation. This review integrates recent cryo‐electron microscopy (cryo‐EM) structures and single‐molecule biophysical data to reconcile competing models of substrate translocation.
Stavros Azinas, Marta Carroni
wiley   +1 more source

An Adapted Rotating Disk Electrode Setup to Test Nonstandard‐Disk Electrodes: On the Enhanced Hydrogen Evolution Performance of Model Dewetted Pt Nanoparticles Versus Pt Thin Films under Hydrodynamic Conditions

ChemElectroChem
A common approach to test electrocatalyst nanoparticles (NPs) for electrolyzers and fuel cells is to deposit catalyst particles (e.g., Pt/carbon) onto standard disk electrodes (e.g., glassy carbon) by making use of inks based on binders (ionomers such as
Shreyas Harsha, Lasse Wichmann, Guido Mul, Marco Altomare   +3 more
doaj   +1 more source

Shallow‐Water Tsunami Deposits: Evidence From Sediment Cores and Numerical Wave Propagation of the 1601 CE Lake Lucerne Event

Geochemistry, Geophysics, Geosystems, 2021
The 1601 CE earthquake (Mw ca. 5.9) in “Unterwalden,” Central Switzerland, triggered multiple subaqueous mass movements and a subaerial rockfall that generated tsunami waves with run‐up heights of up to 4 m and several hundred meters of inundation along ...
Valentin Nigg, Paola Bacigaluppi, David F. Vetsch, Hendrik Vogel, Katrina Kremer, Flavio S. Anselmetti   +5 more
doaj   +1 more source

Predicting the depositional environments and transportation mechanisms of sediments using granulometric parameters, bivariate and multivariate analyses [PDF]

, 2019
Grain size distribution and classes present in sedimentary rocks are responsive to the physical changes of the transporting media and the basin of deposition.
Ikhane, Phillips R., Oladipo, Olajide Vincent, Oyebolu, Olalekan Olayiwola   +2 more
core   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Propagation and deposition of stony debris flows at channel confluences [PDF]

, 2015
The fluid dynamics of stony debris flows generated in two small tributaries adjacent to each other and flowing into a main receiving channel was analyzed experimentally at a laboratory scale.
Foti, E., Lanzoni, Stefano, Stancanelli, LAURA MARIA   +2 more
core   +1 more source

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

Molecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau, Leonor Garcia, Hugo Arnold, Antonija Hanžek, Maialen Arrieta, Laurent R Gauthier, Christine Granotier‐Beckers, François D Boussin, Amaury Herbet, Marie Hautière, Valentin Asei‐Ceschino, Clémentin Jacques, Laura Brard, Thomas Harnois, Valérie Coronas, Bruno Constantin, Aurélien Chatelier, Jean Chemin, Serge Urbach, Martial Seveno, Szimonetta Hideg, Chantal Ripoll, Kasandra Aguilar‐Cázarez, Min Zheng, Guo‐Hao Huang, Sheng‐Qing Lv, Lei Zhang, Philippe Rondard, Laurent Prezeau, Jean‐Philippe Pin, Hugues Duffau, Luc Bauchet, Valérie Rigau, Franck Denat, Charles Truillet, Didier Boquet, Jean‐Philippe Hugnot   +36 more
wiley   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

True Volumes of Slope Failure Estimated From a Quaternary Mass‐Transport Deposit in the Northern South China Sea

Geophysical Research Letters, 2018
Submarine slope failure can mobilize large amounts of seafloor sediment, as shown in varied offshore locations around the world. Submarine landslide volumes are usually estimated by mapping their tops and bases on seismic data.
Qiliang Sun, Tiago M. Alves, Xiangyang Lu, Chuanxu Chen, Xinong Xie   +4 more
doaj   +1 more source

Mass-transport deposits on Mediterranean continental margins

, 2007
Extensive mass transport deposits and multiple slide scars testify widespread and recurrent submarine sediment failures occurring during the late Quaternary on the SW-Adriatic and SE-Sicilian margins. These mass movements and their consequences contributed to shape the continental slopes and fill the basins with characteristic signatures ...
openaire   +2 more sources