Results 91 to 100 of about 227,062 (308)

Promiscuous stimulation of HSP70 ATPase activity by parasite‐derived J‐domains

open access: yesFEBS Open Bio, EarlyView.
The malaria parasite Plasmodium falciparum exports three highly homologous yet functionally divergent J‐domain proteins into human erythrocytes. Here, we show that J‐domains isolated from all three proteins effectively stimulate the ATPase activity of both endogenous host and exported parasite HSP70 chaperones.
Julian Barth   +6 more
wiley   +1 more source

Interfacial Crystallization within Liquid Marbles

open access: yesCondensed Matter, 2020
We report interfacial crystallization in the droplets of saline solutions placed on superhydrophobic surfaces and liquid marbles filled with the saline. Evaporation of saline droplets deposited on superhydrophobic surface resulted in the formation of cup-
Edward Bormashenko   +3 more
doaj   +1 more source

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

open access: yesFEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Angular Momentum Transport via Internal Gravity Waves in Evolving Stars [PDF]

open access: yes, 2014
Recent asteroseismic advances have allowed for direct measurements of the internal rotation rates of many sub-giant and red giant stars. Unlike the nearly rigidly rotating Sun, these evolved stars contain radiative cores that spin faster than their ...
Brown, Ben   +3 more
core   +2 more sources

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

open access: yesFEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane   +11 more
wiley   +1 more source

Dynamic Permeability Related to Greisenization Reactions in Sn-W Ore Deposits: Quantitative Petrophysical and Experimental Evidence

open access: yesGeofluids, 2019
Massive greisens are commonly associated with Sn-W mineralization and constitute low-grade high-tonnage deposits. The formation of this type of deposit results from an intense pervasive metasomatic alteration involving a major fluid and mass transfer ...
Gaëtan Launay   +5 more
doaj   +1 more source

Pharmacological inhibition of the PERK pathway modulates hepatocellular carcinoma growth and immune signaling

open access: yesFEBS Open Bio, EarlyView.
Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero   +5 more
wiley   +1 more source

Transverse Instability of Avalanches in Granular Flows down Incline [PDF]

open access: yes, 2005
Avalanche experiments on an erodible substrate are treated in the framework of ``partial fluidization'' model of dense granular flows. The model identifies a family of propagating soliton-like avalanches with shape and velocity controlled by the ...
Eric Clément   +5 more
core   +1 more source

Risk Prediction Models for Recurrence After Curative Treatment of Early‐Stage or Locally Advanced Lung Cancer: A Systematic Review

open access: yesAging and Cancer, EarlyView.
This systematic review synthesizes prognostic models for survival and recurrence in resected non‐small cell lung cancer. While many models demonstrate moderate to good discrimination, few are externally validated and reporting quality is variable, limiting clinical applicability and highlighting the need for robust, transparent model development ...
Evangeline Samuel   +4 more
wiley   +1 more source

IMPROVING THE METHOD OF OPEN-PIT LIGNITE DEPOSITS DEVELOPMENT IN UKRAINE [PDF]

open access: yes, 2018
Subject of the research is open-pit mining concerning a full- field industrial development of a number of lignite deposits; feasibility study has been performed for them as for the efficient environmental friendly processing of coal and associated ...
Adamchuk, A.A.   +11 more
core  

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