Results 161 to 170 of about 3,550,191 (258)

Adverse events following immunization during COVID-19 mass vaccination campaigns in the Democratic Republic of Congo: Findings from active safety surveillance. [PDF]

PLoS One
Kayumba K, Duga A, Papa Fallah M, Tshidibi C, Lubaki N, Coulibaly B, Djoudalbaye B, Nora Sylvana E, Sembuche SL, Tilahun T, Jibril M, Kilowe C, Kuba A, Mafwila Lusala A, Dereje N, Ndembi N, Raji T, Ngongo N.   +17 more
europepmc   +1 more source

Somatic Evolution of a Germline Antibody Expands its Breadth to Neutralize Early SARS‐CoV‐2 Omicron Variants

Advanced Science, EarlyView.
Engineering of the 148‐germline (148‐GL) antibody reveals a roadmap for overcoming SARS‐CoV‐2 viral escape. By introducing four specific somatic hypermutations, the resulting 148‐M4 variant restores potent neutralization against Omicron BA.1 and BA.4/5.
Huibin Lv, Ziqi Feng, Qi Wen Teo, Chunke Chen, Akshita B. Gopal, Danbi Choi, Timothy J. C. Tan, Yun Sang Tang, Lewis Siu, Armita Nourmohammad, Roberto Bruzzone, Ian A. Wilson, Meng Yuan, Nicholas C. Wu, Chris K. P. Mok   +14 more
wiley   +1 more source

Assessment of Population Immunity Against Peste des Petits Ruminants in Goats and Sheep in India After the Second Annual Mass Vaccination Implemented Under the National PPR Eradication Programme. [PDF]

Viruses
Vinod Kumar K, Ojha R, Deshpande R, Priya S, Goudar AL, Ayesha U, Malini P, Bokade PP, Asha A, Deekshitha G, Dsouza AH, Pal A, Dakshitha A, Harshitha SK, Swathi M, Hemanth RA, Archudhan L, ChandraSekar S, Suresh KP, Govindaraj G, Shivasharanappa N, Krishnamoorthy P, Nayak S, Felix N, Gulati BR, Parida S, Balamurugan V.   +26 more
europepmc   +1 more source

Multi‐regional Organoid Biobank Reveals FAK‐ACSL1‐Driven Doxorubicin‐Resistance and Predictive Biomarkers in Breast Cancer

Advanced Science, EarlyView.
This study established a high‐quality organoid biobank derived from 68 tumor sites across 50 Chinese patients, elucidated the drug sensitivity‐based molecular subtyping in breast cancer, and revealed a novel mechanism of drug resistance mediated by the FAK‐ACSL1 pathway.
Hao Xu, Zhijun Qin, Jiapeng Yang, Baoyuan Zhang, Manqing Cao, Peng Wang, Zaiqi Wang, Jinghui Cheng, Lei Wang, Hong Liu, Hui Yang   +10 more
wiley   +1 more source

Single‐cell Transcriptome Profiling Reveals Gene Regulatory Networks and Key Genes in the Root Epidermis and Cortical Cells Associated with Early Nodulation in Glycine Max

Advanced Science, EarlyView.
Single‐cell transcriptomics of soybean roots soon after rhizobial inoculation reveals epidermal and cortical cell‐specific programs and gene‐regulatory networks acting in symbiosis establishment. We identify an ethylene‐driven regulatory circuit involving WRKY6.3/6.4 transcription factors targeting select Nod19 genes that promotes infection‐thread ...
Yongbin Zhuang, Yu Geng, Xinyu Guo, Chen Wang, Yongjing Sun, Luqi Liu, Li Liu, QianQian Gao, XinFang Zhu, Hongxiang Cao, Gengshuo Zhang, Yunxia Liu, Guobin Zhang, Baoyin Chen, Jinfei Zhang, Xin Hou, Xiaoming Li, Dajian Zhang   +17 more
wiley   +1 more source

Trend of COVID-19 Pandemic in Italy During the Summers 2020 (Before Mass Vaccination), 2021 (After Primary Mass Vaccination) and 2022 (After Booster Mass Vaccination): A Real-World Study Based on a Population of 58,85 Million People

, 2023
Roncati L, Bartolacelli G, Galeazzi C, Caramaschi S.   +3 more
europepmc   +1 more source

Genomic epidemiology of Vibrio cholerae during a mass vaccination campaign of displaced communities in Bangladesh. [PDF]

Nat Commun, 2023
Taylor-Brown A, Afrad MH, Khan AI, Lassalle F, Islam MT, Tanvir NA, Thomson NR, Qadri F.   +7 more
europepmc   +1 more source

A Pan‐Methylome Framework for Population‐Scale Bacterial Epigenomics

Advanced Science, EarlyView.
A scalable quantitative framework unlocks population‐level comparative epigenomics in bacteria. By transforming site‐level data into standardized traits, this approach reconstructs methylation‐informed phylogenies and defines the core epigenome.
Bin Ma, Huimin Gong, Ran Zhuo, Zaixiao Rao, Yanxi Wan, Mingyang Wang, Zahra Zeinalzadeh, Yuan Gao, Aohan Guan, Xinrun Li, Wanting Chen, Xiliang Wang, Yun Wan, Sihua Zhang, Yuncai Xiao, Qi Huang, Paul R. Langford, Xiangru Wang, Rui Zhou, Rui Luo, Hongbo Zhou, Chengliang Zhu, Hui Jin   +22 more
wiley   +1 more source

Bioética e vacinação infantil em massa

Revista Bioética
As vacinas são consideradas como uma das maiores conquistas da humanidade no controle e erradicação de doenças infectocontagiosas e também uma das técnicas biomédicas mais polêmicas e de maior controvérsia considerando os riscos de efeitos adversos e a ...
Sérgio de Castro Lessa, José Garrofe Dórea   +1 more
doaj  

Effectiveness of Follow-Up Mass Vaccination Campaigns Against Measles and Rubella to Mitigate Epidemics in West Africa (2024-2025): A Cross-Sectional Analysis of Surveillance and Coverage Data. [PDF]

Vaccines (Basel)
Nimpa MM, Bwaka AM, Elime FA, Mouhembe MWN, Bagayoko AN, Munianji EM, Tague C, Kalabudi JL, Mjumbe CK.   +8 more
europepmc   +1 more source