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Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao +13 more
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The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo +8 more
wiley +1 more source
[Mass vaccination against cholera].
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Parents’ malevolent personification of mass vaccination solidifies vaccine hesitancy
Journal of Health Psychology, 2020Parental hesitancy to vaccinate their children derails the success of mass vaccination campaigns. We examined the effect of parents’ personification of the vaccinating agency on vaccine hesitancy (i.e. negative or positive mind change) in 555 parents in a mass wild poliovirus vaccination campaign. Parents were assessed before and after the campaign on
Gal Noyman-Veksler +3 more
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COVID-19 Mass Vaccination Resource Calculator
Applied Clinical Informatics, 2021Abstract Background Despite the recent emergency use authorization of two vaccines for the prevention of the 2019 novel coronavirus (COVID-19) disease, vaccination rates are lower than expected. Vaccination efforts may be hampered by supply, delivery, storage, patient prioritization, administration infrastructure or logistics problems.
Grace E, Pryor +4 more
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Mass Vaccination: When and Why
2006With increased demand for smallpox vaccination during the nineteenth century, vaccination days--early mass vaccination campaigns--were conducted over time-limited periods to rapidly and efficiently protect maximum numbers of susceptible persons. Two centuries later, the challenge to rapidly and efficiently protect populations by mass vaccintion ...
D L, Heymann, R B, Aylward
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Mass Psychogenic Illness After Vaccination
Drug Safety, 2003When vaccines are administered to groups, the physical reactions of the recipients may be similar, causing a form of mass reaction, the mechanism for which is the same as that for mass reactions from other causes. These phenomena have been categorised as mass psychogenic illness (MPI), and have been defined as the collective occurrence of a ...
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2019
While the eradication of smallpox has long been documented, not many know the Chinese roots of this historic achievement. This book examines the People's Republic of China's public health campaigns of the 1950s to explain just how China managed to inoculate almost six hundred million people against this and other deadly diseases.
openaire +1 more source
While the eradication of smallpox has long been documented, not many know the Chinese roots of this historic achievement. This book examines the People's Republic of China's public health campaigns of the 1950s to explain just how China managed to inoculate almost six hundred million people against this and other deadly diseases.
openaire +1 more source

