Results 241 to 250 of about 271,644 (300)

IGFBP5 Restores Endometrial Receptivity and Rescues Implantation Failure in Polycystic Ovary Syndrome

open access: yesAdvanced Science, EarlyView.
Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao   +13 more
wiley   +1 more source

Development and Structural Characterization of UTE‐156, a Covalent Inhibitor of the VCP/p97 AAA+ ATPase

open access: yesAdvanced Science, EarlyView.
The AAA+ ATPase Valosin‐containing protein (VCP/p97) regulates protein homeostasis by unfolding ubiquitinated substrates. Here, we describe UTE‐156, a novel irreversible covalent inhibitor that modifies Cys522 in the D2 ATPase motor domain. Although its pharmacochemical limitations preclude immediate therapeutic use, UTE‐156 serves as a valuable ...
Daniela Tamayo‐Jaramillo   +8 more
wiley   +1 more source

[Mass vaccination against cholera].

open access: yesTidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 2013
openaire   +1 more source
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Parents’ malevolent personification of mass vaccination solidifies vaccine hesitancy

Journal of Health Psychology, 2020
Parental hesitancy to vaccinate their children derails the success of mass vaccination campaigns. We examined the effect of parents’ personification of the vaccinating agency on vaccine hesitancy (i.e. negative or positive mind change) in 555 parents in a mass wild poliovirus vaccination campaign. Parents were assessed before and after the campaign on
Gal Noyman-Veksler   +3 more
openaire   +2 more sources

COVID-19 Mass Vaccination Resource Calculator

Applied Clinical Informatics, 2021
Abstract Background Despite the recent emergency use authorization of two vaccines for the prevention of the 2019 novel coronavirus (COVID-19) disease, vaccination rates are lower than expected. Vaccination efforts may be hampered by supply, delivery, storage, patient prioritization, administration infrastructure or logistics problems.
Grace E, Pryor   +4 more
openaire   +2 more sources

Mass Vaccination: When and Why

2006
With increased demand for smallpox vaccination during the nineteenth century, vaccination days--early mass vaccination campaigns--were conducted over time-limited periods to rapidly and efficiently protect maximum numbers of susceptible persons. Two centuries later, the challenge to rapidly and efficiently protect populations by mass vaccintion ...
D L, Heymann, R B, Aylward
openaire   +2 more sources

Mass Psychogenic Illness After Vaccination

Drug Safety, 2003
When vaccines are administered to groups, the physical reactions of the recipients may be similar, causing a form of mass reaction, the mechanism for which is the same as that for mass reactions from other causes. These phenomena have been categorised as mass psychogenic illness (MPI), and have been defined as the collective occurrence of a ...
openaire   +2 more sources

Mass Vaccination

2019
While the eradication of smallpox has long been documented, not many know the Chinese roots of this historic achievement. This book examines the People's Republic of China's public health campaigns of the 1950s to explain just how China managed to inoculate almost six hundred million people against this and other deadly diseases.
openaire   +1 more source

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