Results 41 to 50 of about 3,902,706 (298)
After Gunshot: A Qualitative Evidence Synthesis on Community Recovery from Mass Violence
Incidents of mass violence, defined as occurring in a public place with at least four fatalities and not related to domestic violence or other criminal activity, have left scars on the social psyche of communities that have survived and witnessed them ...
Bleoaja Cayla
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg +14 more
wiley +1 more source
International criminal investigations are not only legal exercises but epistemological and cultural ones. Drawing on the author’s work across human rights practice, international tribunals, journalism and historical scholarship, this essay observes that ...
Thijs B. Bouwknegt
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Studying Mass Violence: Pitfalls, Problems, and Promises
This article examines some of the main pitfalls, problems, and promises of genocide research. It ar- gues that genocide is a viable academic concept if protected from moral, legal, political, and emo- tional constraints. It should be approached in a dispassionate, amoral, non-juridical, and apolitical way.
openaire +3 more sources
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source
Revisiting Ruddick: Feminism, pacifism and non-violence [PDF]
This article explores feminist contentions over pacifism and non-violence in the contextof the Greenham Common Peace Camp in the 1980s and later developments offeminist Just War Theory.
HUTCHINGS, KJ, FRAZER, E
core +1 more source
Describing a “mass shooting”: the role of databases in understanding burden
Background The mass shooting phenomenon has gained much attention lately as this form of gun violence appears to increase in frequency. Although many organizations collect information on mass shootings (fatal and nonfatal injuries), no federal definition
Marisa Booty +4 more
doaj +1 more source
During the last decade, especially with the Russian aggression against Ukraine, armed conflicts and other forms of organized violence increased in volume and public discourse.
Ludger Pries
doaj +1 more source

