Results 51 to 60 of about 3,902,706 (298)
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Revista de Antropología Social, 2015 Focusing on the recent experiences of the Wayuu indigenous people of Colombian Guajira, I analyze the ways in which memory practices in situations of mass violence are intertwined with the politics of multiculturalism and expansion of transnational ...
Carlos Arturo Salamanca
doaj +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
, 2020 The experiences of Korean comfort girls-women are a paradigmatic example of how military sexual violence can obliterate the dignity of women and shame them into nonexistence.
core +1 more source
The role of domestic violence in fatal mass shootings in the United States, 2014–2019
Injury Epidemiology, 2021 Background Fatal mass shootings, defined as four or more people killed by gunfire, excluding the perpetrator, account for a small percentage of firearm homicide fatalities.
Lisa B. Geller +2 more
doaj +1 more source
Translophagy—A potential link between autophagy impairment and translational errors
FEBS Letters, EarlyView.Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk +11 more
wiley +1 more source
FEBS Letters, EarlyView.Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell +2 more
wiley +1 more source
ABUAD Journal of the Humanities-AGIDIGBO, 2014 Contlict situations in post-colonial Nigeria, ranging from communal violence, indigenes/settlers crises, environmental disasters, electoral violence, political upheavals to terrorist insurgency and the attendant increasing volume of media attention they
Mathew Olusola Ojo +2 more
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
Journal for Deradicalization, 2015 This paper considers the conceptual and empirical merits of Ernest Becker’s analysis of radicalization and mass violence. Starting with several cases showing a clear link between exposure to traumatic events and violence, Ernest Becker’s idea that mass ...
Mark Dechesne
doaj