Optimization of Enzyme-Assisted Ultrasonic Extraction of a Quercetin-Containing Crude Extract from <i>Sophora japonica</i> Flower Buds and Evaluation of Its In Vitro Antioxidant and Antibacterial Activities. [PDF]
Li Y +6 more
europepmc +1 more source
A minimal cellulosome‐like system in Cellulosilyticum lentocellum
Cellulose‐degrading bacteria typically use cellulosomes, large multi‐enzyme complexes on a scaffold protein. In Cellulosilyticum lentocellum, we characterise a far smaller arrangement, a single scaffold bound to one cellulase through a single cohesin‐dockerin interaction.
John Allan +2 more
wiley +1 more source
BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley +1 more source
One-Step Synthesis of Dihydropyrroloquinazolinone Alkaloid Natural Products: <i>S</i>‑(-)- and <i>R</i>‑(+)-Vasicinone and Their Novel Analogues. [PDF]
Khaliq T, Kaur V.
europepmc +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
Cascade Valorization of Brewer's Spent Grain Residues Through Green Solvent Extractions and Subsequent Thermochemical Conversion to Activated Carbon Adsorbers. [PDF]
Bleus D +3 more
europepmc +1 more source
Functional screening identified PcSyn14890, a cyanobacteria‐specific protein that enhances growth and stress resistance in E. coli and Synechocystis PCC6803. Although we expected it to function as a molecular chaperone, it was unable to protect against thermal aggregation of GAPDH.
Akiyo Yamada +7 more
wiley +1 more source
Efficiency Improvement and SEM Visualization of Enzymatic Hydrolysis-Based Valorization of Oat Hulls. [PDF]
Kashcheyeva EI, Budaeva VV.
europepmc +1 more source
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho +4 more
wiley +1 more source
Strain-dependent resistance of yellow mealworm (Coleoptera: Tenebrionidae) to bacterial infection with and without probiotic supplementation. [PDF]
Saint-Jacques G +6 more
europepmc +1 more source

