Results 51 to 60 of about 319,282 (323)
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source
A Study of Abundance Patterns in the Sextans and Sculptor Dwarf Spheroidal Galaxies
The Astrophysical JournalIn this work, we employ a multicomponent decomposition model to study the Sextans and Sculptor dwarf spheroidal galaxies, which have distinct evolutionary histories.
Shuaishuai Yang +3 more
doaj +1 more source
Young, Massive Star Candidates Detected throughout the Nuclear Star Cluster of the Milky Way
, 2012 Aims. Young, massive stars have been found at projected distances R < 0.5 pc from supermassive black hole, Sgr A* at the center of our Galay. In recent years, increasing evidence has been found for the presence of young, massive stars also at R > 0.5 pc.
Nishiyama, Shogo, Schödel, Rainer
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Dust around Massive Stars Is Agnostic to Galactic Environment: New Insights from PHAT/BEAST
The Astrophysical JournalResolving the environments of massive stars is crucial for understanding their formation mechanisms and their impact on galaxy evolution. An important open question is whether massive stars found in diffuse regions outside spiral arms formed in situ or ...
Christina Willecke Lindberg +4 more
doaj +1 more source
Hot Stars in Stellar Populations of Galaxies
GalaxiesStar-forming galaxies are hosts of dominant populations of recently formed, hot, massive stars, which give rise to conspicuous stellar spectral features and provide the ionizing fluxes. Strong outflows of these stars shape their properties.
Claus Leitherer
doaj +1 more source
Rethinking plastic waste: innovations in enzymatic breakdown of oil‐based polyesters and bioplastics
FEBS Open Bio, EarlyView.Plastic pollution remains a critical environmental challenge, and current mechanical and chemical recycling methods are insufficient to achieve a fully circular economy. This review highlights recent breakthroughs in the enzymatic depolymerization of both oil‐derived polyesters and bioplastics, including high‐throughput protein engineering, de novo ...
Elena Rosini +2 more
wiley +1 more source
Optical images of massive boson stars with nonlinear electrodynamics
European Physical Journal C: Particles and FieldsThis study investigates the optical imaging characteristics of massive boson stars based on the Einstein–Klein–Gordon theory coupled to nonlinear electrodynamics.
Xiao-Xiong Zeng +3 more
doaj +1 more source
The young stellar population of IC 1613. III. New O-type stars unveiled by GTC-OSIRIS [PDF]
, 2012 Recent findings hint that the winds of massive stars with poorer metallicity than the SMC may be stronger than predicted by theory. Besides calling the paradigm of radiation driven winds into question, this result would impact the predicted evolutionary ...
Garcia, Miriam, Herrero, Artemio
core +1 more source
Thrombolytic proteins profiling: High‐throughput activity, selectivity, and resistance assays
FEBS Open Bio, EarlyView.We present optimized biochemical protocols for evaluating thrombolytic proteins, enabling rapid and robust screening of enzymatic activity, inhibition resistance, and fibrin affinity, stimulation, and selectivity. The outcome translates to key clinical indicators such as biological half‐life and bleeding risk. These assays streamline the development of
Martin Toul +3 more
wiley +1 more source