Molecular Carcinogenesis, EarlyView.ABSTRACT Lung cancer is the leading cause of cancer‐related mortality worldwide, with LUAD being characterized by high incidence and mortality rates. Despite the use of various treatments, including surgery, chemotherapy, immunotherapy, and molecular targeted therapy, the prognosis in LUAD patients remains unfavorable.
Jingshun Zhang +7 more
wiley +1 more source
Autologous blood pleurodesis for surgical pneumothorax and outcome with multimodal cancer treatment in a dog with primary pulmonary mast cell tumor. [PDF]
Clin Case Rep, 2022 Shinsako D +3 more
europepmc +1 more source
Med Research, EarlyView.This review summarizes the immuno‐inflammatory mechanisms driving the pathogenesis of osteoarthritis (OA), extending beyond the traditional view of OA as a purely degenerative disease to incorporate immune cell infiltration, inflammatory factor release, and the formation of a chronic low‐grade inflammatory microenvironment.
Qingqiang Lei +9 more
wiley +1 more source
Mast Cell-Tumor Interactions: Molecular Mechanisms of Recruitment, Intratumoral Communication and Potential Therapeutic Targets for Tumor Growth. [PDF]
Cells, 2022 Segura-Villalobos D +9 more
europepmc +1 more source
Neuroprotection, EarlyView.ECM, extracellular matrix; BDNF, brain‐derived neuroptrophic factor; FGF, fibroblast growth factor; VEGF, vascular endothelial growth factor. Abstract Heparan sulfate, a structurally diverse glycosaminoglycan that is abundant in the central nervous system (CNS), orchestrates essential processes fundamental to neural plasticity, neurorepair, and ...
Mozammel H. Bhuiyan +3 more
wiley +1 more source
The role of the host—Neutrophil biology
Periodontology 2000, EarlyView., 2023 Abstract Neutrophilic polymorphonuclear leukocytes (neutrophils) are myeloid cells packed with lysosomal granules (hence also called granulocytes) that contain a formidable antimicrobial arsenal. They are terminally differentiated cells that play a critical role in acute and chronic inflammation, as well as in the resolution of inflammation and wound ...
Iain L. C. Chapple +4 more
wiley +1 more source
Histological and immunohistochemical features of cutaneous mast cell tumor in six captive four-toed hedgehogs (Atelerix albiventris). [PDF]
J Vet Med Sci, 2022 Son NV +5 more
europepmc +1 more source
Comparative Evaluation of the Mast Cells between Oral and Cutaneous Squamous Cell Carcinoma
Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2017 BACKGROUND AND OBJECTIVE: It has been mentioned that mast cells may help to tumor invasion. According to different aggressive behavior of oral squamous cell carcinoma (OSCC) compared to cutaneous SCC (CSCC), the aim of this study was to compare mast ...
E Mohammadnia Sarvi +3 more
doaj
Differential Transcriptomic Profiles Following Stimulation with Lipopolysaccharide in Intestinal Organoids from Dogs with Inflammatory Bowel Disease and Intestinal Mast Cell Tumor. [PDF]
Cancers (Basel), 2022 Sahoo DK +11 more
europepmc +1 more source
Phytotherapy Research, EarlyView.Schematic summary of the experimentally supported mechanism of DHL in hepatocellular carcinoma. Dehydrocostus lactone (DHL), a sesquiterpene lactone derived from Aucklandia lappa, directly engages protein tyrosine kinase 7 (PTK7), as supported by molecular docking, CETSA, and DARTS assays.
Xiwen Fan +8 more
wiley +1 more source