Results 191 to 200 of about 77,966 (263)

Associations Between Otic Cytological Findings and Clinical Severity by Pathogen Group in Canine Otitis Externa: A Retrospective Study of 318 Cases

Veterinary Dermatology, EarlyView.
Background: Otic cytological assessment is routinely used in canine otitis externa (OE) to assess microbial burden and inflammation. Evidence that cytological findings are associated with clinical severity, particularly by pathogen group, remains limited.
Eun‐Seo Shin, Soh‐Yoon Kang, Min‐Sun Kim, Cheol‐Yong Hwang   +3 more
wiley   +1 more source

Novel volume‐electron microscopic ultrastructural analysis of gastrointestinal excitability associated with calcium–activated chloride channels

The Journal of Physiology, EarlyView.
Abstract figure legend Immunohistochemistry, electrophysiology and pharmacology are useful tools for understanding protein and channel expression and physiological reactions of calcium‐activated chloride channels (CaCCs). Conventional transmission electron microscopy has provided useful 2‐D information on organelle arrangement, localization and ...
Hiromi Tamada
wiley   +1 more source

Plasma PlGF as a Potential Biomarker in Ramucirumab‐Based Second‐Line Therapy for Advanced Gastroesophageal Adenocarcinoma: Exploratory Biomarker Analysis from the Phase II Part of the RAMIRIS Trial

International Journal of Cancer, Volume 159, Issue 7, Page 1817-1828, 1 October 2026.
Antiangiogenic treatment with ramucirumab is a standard second‐line option in advanced gastric and gastroesophageal junction adenocarcinoma. However, reliable biomarkers are currently lacking. This exploratory biomarker analysis of the RAMIRIS trial suggests that elevated baseline and early on‐treatment levels of the pro‐angiogenic placental growth ...
Jurek Hille, Sylvie Lorenzen, Claudia Pauligk, Victoria Gensch, Peter Thuss‐Patience, Eray Goekkurt, Thomas Ettrich, Florian Lordick, Carsten Bokemeyer, Christian Müller, Peter Reichardt, Martin Sökler, Daniel Pink, Stefan Probst, Thorsten O. Goetze, Salah E. Al‐Batran, Sonja Loges, Melanie Janning   +17 more
wiley   +1 more source

Immunomodulation of the Prostate Tumor Microenvironment Following Inorganic Arsenic Exposure

Journal of Applied Toxicology, Volume 46, Issue 9, Page 3274-3287, September 2026.
ABSTRACT The tumor microenvironment (TME) influences prostate cancer (PCa) progression through stromal and immune interactions. Adipose‐derived mesenchymal stromal cells (ASCs) modulate immune tone, while inorganic arsenic (iAs), a widespread toxicant, is linked to immune suppression and carcinogenesis.
Joseph J. Shearer, Cosette Rivera‐Cruz, Alexandre M. B. Cavalca, Carlos Eduardo Fonseca‐Alves, Marxa L. Figueiredo   +4 more
wiley   +1 more source

Integrating Tumor Budding and the Invasive-Front Microenvironment in Colorectal Carcinoma: An Exploratory Histopathological Score-Based Association Study. [PDF]

Int J Mol Sci
Zuccalà V, Fiorentino V, Martorana TM, Ricciardi G, Tralongo P, Ciappina G, Abbonante V, Ammendola M, Berretta M, Fadda G, Martini M, Ieni A.   +11 more
europepmc   +1 more source

Long‐Term Prognosis and Immunotranscriptomic Landscape in Esophageal Squamous Cell Carcinoma With Different Pathological Responses to Neoadjuvant Chemoradiotherapy: A Retrospective Cohort Study

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This study comprehensively characterizes the long‐term prognosis and immunotranscriptomic landscape associated with different tumor regression grades (TRGs) in esophageal squamous cell carcinoma (ESCC) following neoadjuvant chemoradiotherapy. By integrating bulk RNA‐seq, single‐cell transcriptomics, and multiplexed immunohistochemistry, we demonstrate ...
Jianye Yuan, Zelin Weng, Xinke Zhang, Fangqi Deng, Zihui Tan, Jian Zhong, Rui Chen, Xiuying Xie, Xiaodan Lin, Ting Lin, Yan Huang, Qianwen Liu, Jing Wen, Jianhua Fu   +13 more
wiley   +1 more source

What Is Your Diagnosis? Cutaneous Mass in a Dog

Veterinary Clinical Pathology, EarlyView.
Ester Quilez, Shannon L. Donahoe
wiley   +1 more source

Tumor Invasive Border Index (TIBI) in colorectal cancer: linking infiltrative morphology to molecular insights

The Journal of Pathology, Volume 270, Issue 1, Page 114-128, September 2026.
Abstract Tumor border configuration influences colorectal cancer (CRC) prognosis, yet its molecular determinants remain unclear and existing assessment criteria have faced challenges with reproducibility. We introduce the Tumor Invasive Border Index (TIBI), a novel and reproducible method that quantifies the proportion of tumor stroma and adipose ...
Akseli Kehusmaa, Jouni Härkönen, Huayi Li, Päivi Sirniö, Ville K Äijälä, Henna Karjalainen, Meeri Kastinen, Vilja V Tapiainen, Tuomo Mantere, Vesa‐Matti Pohjanen, Hanna Elomaa, Onni Sirkiä, Nicolas Pasquier, Maarit Ahtiainen, Olli Helminen, Erkki‐Ville Wirta, Taneli T Mattila, Outi Lindgren, Janette Savela, Jukka Rintala, Sanna Meriläinen, Juha Saarnio, Tero Rautio, Toni T Seppälä, Jan Böhm, Jukka‐Pekka Mecklin, Markus J Mäkinen, Anne Tuomisto, Johanna Ivaska, Juha P Väyrynen   +29 more
wiley   +1 more source

AllergoOncology: Emerging Translational and Clinical Significance of Basophils and Mast Cells in Cancer. [PDF]

Clin Transl Allergy
Alder J, Lacy KE, Josephs DH, Spicer J, Bax HJ, Karagiannis SN, Chauhan J.   +6 more
europepmc   +1 more source

What Is Your Diagnosis? Leukocytosis With Abnormal WDF and WNR Scattergrams From the Sysmex XN‐1000V in a Dog

Veterinary Clinical Pathology, EarlyView.
Javier Martínez‐Caro, Marta Lemos, Josep Pastor   +2 more
wiley   +1 more source