Results 101 to 110 of about 133,458 (260)

Tau Aggregate Imaging and Transcriptomics of Alzheimer's Disease Brain at Different Stages of Disease

open access: yesAdvanced Science, EarlyView.
The protein aggregates and gene expression in the middle temporal gyrus (MTG) and somatosensory cortex (SOM) of the postmortem brains of 13 Alzheimer's disease patients were studied in detail, revealing that small hyperphosphorylated tau aggregates increase with Braak stage driven by microglial inflammation.
Elizabeth A. English   +9 more
wiley   +1 more source

Differential Gene Expression of Human Mast cell Activation Reveals Gene profiles of Innate and Adaptive Immunity. [PDF]

open access: yes, 2007
High-density oligonucleotide microarray is a promising approach for high throughput analysis. It has been extensively used in many areas of biomedical research.
Alirio Jose Melendez   +3 more
core   +1 more source

Population trends of house mice during tussock mast seeding on Auckland Island

open access: yes, 2023
House mice (Mus musculus) are an invasive species on Auckland Island in the New Zealand subantarctic and planning for their eradication is underway. Mast seeding events cause rodent populations to irrupt, though little is known about this phenomenon in ...
Sagar, Rachael   +3 more
core   +1 more source

An Injectable Metal‐Drug Supramolecular Condensate Enables Radiosensitization and Systemic Antitumor Immunity for Post‐Surgical Osteosarcoma Therapy

open access: yesAdvanced Science, EarlyView.
This work designed an injectable metal‐drug supramolecular condensate formed from hafnium ions and alendronate (Hf‐ALN) and loaded with the COX‐2 inhibitor celecoxib (CXB) for synergistic radioimmunotherapy of postoperative osteosarcoma. Mechanistically, upon X‐ray irradiation, Hf enhances radiation energy deposition, ROS generation, and DNA damage ...
Tianhua Xiao   +12 more
wiley   +1 more source

Influence of forest stand on the reproductive biology of the edible dormouse Glis glis

open access: yesFolia Oecologica
In this study, carried out between 2018 and 2024, we investigated how stand species composition, stand age, and tree mast cycles affect selected life functions of the edible dormouse.
Moska Magdalena   +3 more
doaj   +1 more source

Data from: Mast seeding patterns are asynchronous at a continental scale

open access: yes, 2020
Resource pulses are rare events with a short duration and high magnitude that drive the dynamics of both plant and animal populations and communities. Mast seeding is perhaps the most common type of resource pulse that occurs in terrestrial ecosystems ...
Greene, David   +3 more
core   +1 more source

Leptin May Promote Eosinophilic CRSwNP Progression by Enhancing Eosinophil Chemotaxis and Angiogenesis Under a Type 2 Inflammatory Milieu

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Chronic rhinosinusitis with nasal polyp (CRSwNP) is a heterogeneous Type 2 inflammatory disease characterized by enhanced eosinophilic infiltration. Both innate and adaptive immunity are involved in the onset and progression of CRSwNP.
Yuki Sonoda   +4 more
wiley   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

open access: yesAnimal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang   +11 more
wiley   +1 more source

Intrinsic biotic factors and microsite conditions drive seedling survival in a species with masting reproduction

open access: yesEcology and Evolution, 2019
Seedling recruitment following a masting event, where more fruits are produced in synchrony and intermittently compared with other species, plays a crucial role in determining species diversity and community structure.
Francesco Martini   +2 more
doaj   +1 more source

Dynamics, Mechanisms, and Consequences of Mast Seeding

open access: yesAnnual Review of Ecology, Evolution, and Systematics
Mast seeding is the phenomenon in which perennial plants produce seed crops in highly variable and synchronized pulses. The irregular seed production associated with masting reverberates through food webs, influencing consumer abundance, behavior, life history strategies, and broader ecosystem processes.
Bogdziewicz, Michał   +4 more
openaire   +1 more source

Home - About - Disclaimer - Privacy