Results 41 to 50 of about 7,777 (162)

The landscape of viral associations in human cancers [PDF]

, 2020
Here, as part of the Pan-Cancer Analysis of Whole Genomes (PCAWG) Consortium, for which whole-genome and—for a subset—whole-transcriptome sequencing data from 2,658 cancers across 38 tumor types was aggregated, we systematically investigated potential ...
Alawi, Malik, Borozan, Ivan, Brewer, Daniel S, Cooper, Colin S, Desai, Nikita, Eils, Roland, Ferretti, Vincent, Grundhoff, Adam, Iskar, Murat, Lichter, Peter, Moch, Holger, PCAWG Consortium, PCAWG Pathogens, Sültmann, Holger, Zapatka, Marc   +14 more
core   +3 more sources

Addressing the Health Risks Posed by Adenovirus: A Perspective on Strategies for Prevention and Management. [PDF]

Health Sci Rep
ABSTRACT Background Adenovirus (AdV) is a non‐enveloped virus with a double‐stranded DNA genome that can infect the respiratory and gastrointestinal tracts, as well as cause conjunctivitis. The infection is influenced by the patient's age, environment, temperature, and immunocompromised individuals.
Urmi TJ, Rahman JM, Dewan SMR.
europepmc   +2 more sources

Outbreak of acute respiratory infection among infants in Lisbon, Portugal, caused by human adenovirus serotype 3 and a new 7/3 recombinant strain [PDF]

, 2010
Human adenoviruses (AdVs) typically cause mild illnesses in otherwise healthy hosts. We investigated a pediatric outbreak of acute respiratory infection with fatal outcomes that occurred in Lisbon, Portugal, in 2004.
Andrade, Helena Rebelo de, Brito, Maria João, Calé, Etelvina, Gíria, Marta, Pereira, Cristiana, Prudêncio, Ema, Taveira, Nuno   +6 more
core   +6 more sources

Clinical and Epidemiological Insights into a Parainfluenza Virus Type 3 Outbreak in Multiple Myeloma Patients. [PDF]

J Med Virol
ABSTRACT Human parainfluenza virus type 3 (HPIV‐3) can be responsible for mild to severe respiratory infections and hospital epidemics. We investigated an outbreak in a hematology unit. Respiratory viruses were screened using multiplex PCR. HPIV‐3 quantification and whole‐genome sequencing were performed on HPIV‐3 positive respiratory samples. Clinical
Timsit S, Mellon G, Forgeard N, Mercier-Delarue S, Mahjoub N, Euzen V, Harel S, Elessa D, Osinski N, Diaz E, Royer B, Arnulf B, Salmona M, Legoff J.   +13 more
europepmc   +2 more sources

Evaluation of bat adenoviruses suggests co-evolution and host roosting behaviour as drivers for diversity. [PDF]

, 2021
Adenoviruses (AdVs) are diverse pathogens of humans and animals, with several dozen bat AdVs already identified. Considering that over 100 human AdVs are known, and the huge diversity of bat species, many bat AdVs likely remain undiscovered.
Diffo, Joseph, Gillis, Amethyst, Joly, Damien, Lange, Christian, LeBreton, Matthew, McIver, David, Monagin, Corina, Mouiche, Moctar, Ndze, Valantine, Ntumvi, Nkom, Nwobegahay, Julius, Rimoin, Anne, Rubin, Edward, Schneider, Bradley, Takuo, Jean-Michel, Tamoufe, Ubald, Wolfe, Nathan   +16 more
core   +1 more source

Development of novel adenoviral vectors to overcome challenges observed with HAdV-5 based constructs [PDF]

, 2011
Recombinant vectors based on human adenovirus serotype 5 (HAdV-5) have been extensively studied in pre-clinical models and clinical trials over the last two decades.
Julio Alonso-Padilla, Tibor Papp, Győző L Kaján, Mária Benkő, Menzo Havenga, Angelique Lemckert, Balázs Harrach, Andrew H Baker, Harrach, Benkő, Liu, Reddy, Benevento, Reddy, Rux, Bergelson, Wickham, Wolfrum, Arnberg, Burckhardt, Vectors used in gene therapy clinical trials., Appaiahgari, Pearson, Wilson, Chorny, Van Kampen, George, Ranki, Hendrickx, Ilan, Schaack, Aldhamen, Machitani, Appledorn, Perreau, Minamitani, Khare, Lyons, Carlisle, Seiradake, Xu, Khare, Qiu, Waddington, Kalyuzhniy, Vigant, Alba, Jonsson, Lenman, Doronin, Xu, Eichholz, Ganesan, Alemany, Piccolo, Mocanu, Piccolo, Khare, Xu, Lasaro, Zak, Zhang, Barouch, Bradley, Roberts, Gall, Fausther-Bovendo, Sumida, Miyazawa, Teigler, Smith, Molinier-Frenkel, Heemskerk, Hutnick, Tang, Olive, Leen, Joshi, Osada, Perreau, Seregin, Seregin, Fontanellas, Cerullo, Brunetti-Pierri, Seregin, Farrow, McConnell, Belousova, Seregin, Capasso, Green, Doronin, Kreppel, Matsui, Suzuki-Kouyama, Prill, Krasnykh, Zabner, Havenga, Lecollinet, Coughlan, Granio, Parker, Guse, Smith, Nicol, Bruder, Bruder, Baden, Coughlan, Mück-Häusl, Bi, Abbink, Abbink, Mastrangeli, Abrahamsen, Brough, Stone, Sirena, Stone, Seshidhar Reddy, Hemminki, Creech, Vogels, Kuhn, Di, Havenga, Kahl, Vogels, Lemckert, Teigler, Tameris, Ouédraogo, Keefer, Baden, Gilbert, Baden, Zahn, Johnson, Dakin, Alexander, Alexander, Gurwith, Lemiale, Jarecki-Khan, Saderi, Ko, Bangari, Ayalew, Hammond, Tuboly, Fischer, Hu, Greenall, Brake, Lopez-Gordo, Kremer, Soudais, Soudais, Silva, Puig, Fernandes, Tandon, Bangari, Nguyen, Lenaerts, Ying, van Olphen, Zakhartchouk, Cauthen, Reddy, Reddy, Li, Lenaerts, Sharma, Sharma, Roy, Cohen, Xiang, Quinn, Farina, Roy, Colloca, Barnes, O'Hara, Antrobus, Stanley, Tan, Michou, Ojkic, Sheppard, Corredor, Cherenova, Shashkova, Logunov, Both, Xu, Khatri, Hofmann, Löser, Both, Martiniello-Wilks, Tang, Fraser, Bridgeman, Doszpoly, Cortés-Hinojosa, Wigand, Kajon, Guy, Benkö, Lu, Günes, Wellehan, Phan   +215 more
core   +4 more sources

Circumventing antivector immunity: potential use of nonhuman adenoviral vectors [PDF]

, 2014
Adenoviruses are efficient gene delivery vectors based on their ability to transduce a wide variety of cell types and drive high-level transient transgene expression. While there have been advances in modifying human adenoviral (HAdV) vectors to increase
Beard C.W., Benkö M., Cauthen A.N., Crawford-Miksza L., Estrella Lopez-Gordo, Gall J., Gall J.G., Gattoni A., Ginsberg H.S., Haviv Y.S., Hofmann C., Iva I. Podgorski, Kajon A.E., Kanerva A., Kass-Eisler A., Kuriyama S., Mastrangeli A., Michou A.I., Nicholas Downes, Ramon Alemany, Rogozhin V.N., Roy S., Seiradake E., Shmarov M.M., Soudais C., Tutykhina I.L., Wang D.Y., Wohlfart C., Ying B., Zakhartchouk A.N., Zeng Q.   +30 more
core   +3 more sources

Characterization of a Novel Bat Adenovirus Isolated from Straw-Colored Fruit Bat (Eidolon helvum). [PDF]

, 2017
Bats are important reservoirs for emerging zoonotic viruses. For extensive surveys of potential pathogens in straw-colored fruit bats (Eidolon helvum) in Zambia, a total of 107 spleen samples of E. helvum in 2006 were inoculated onto Vero E6 cells.
Fujikura, Daisuke, Hang’ombe, Bernard M., Higashi, Hideaki, Kajihara, Masahiro, Mutemwa, Alisheke, Mweene, Aaron S., Nao, Naganori, Ogawa, Hirohito, Sawa, Hirofumi, Shigeno, Asako, Squarre, David, Takada, Ayato, Yamada, Masao   +12 more
core   +2 more sources

Three novel, multiple recombinant types of species of human mastadenovirus D (HAdV-D 73, 74 & 75) isolated from diarrhoeal faeces of immunocompromised patients.

Journal of General Virology, 2017
E. Hage, A. Dhingra, U. Liebert, Sandra Bergs, T. Ganzenmueller, A. Heim   +5 more
semanticscholar   +2 more sources

New Adenovirus Groups in Western Palaearctic Bats [PDF]

, 2018
In the context of long-term screening for viruses on Western Palaearctic bats, we tested for the presence of adenovirus 1392 oropharyngeal swabs and 325 stool samples taken from 27 bat species.
Aiartza Azurtza, José Ramón, Aznar López, Carolina, Berciano, Jose M., Casas, Inmaculada, Echevarría, Juan E., Falcon, Ana, Garín Atorrasagasti, Ignacio, Ibáñez, Carlos, Iglesias Caballero, María, Juste, Javier, Pozo, Francisco, Ruiz, Guillermo, Vázquez Morón, Sonia   +12 more
core   +5 more sources