Results 121 to 130 of about 1,144,518 (264)

The TESTBREAST journey: Revisiting the importance of early detection by frequent screening of women at high risk of breast cancer

International Journal of Cancer, Volume 157, Issue 4, Page 741-751, 15 August 2025.
What's new? Women who are at high risk of breast cancer (BC), either because of a BRCA1/2 mutation or family history, require more aggressive screening. Here, the authors report on the clinical characteristics of the high‐risk women who developed BC during the TESTBREAST study. Of the 1108 participants, 124 (16.5%) developed breast cancer. Their median
Layla Andour, Sophie C. Hagenaars, Kiki Vangangelt, Janneke Aalberts, Valerie Rebattu, Dorien M. A. Berends van der Meer, Elma Meershoek‐Klein Kranenbarg, Katja N. Gaarenstroom, Christi J. van Asperen, Rob A. E. M. Tollenaar, Wilma E. Mesker, on behalf of the TESTBREAST study team, J. Aalberts, T. M. A. Berends‐van der Meer, S. C. Hagenaars, L. Andour, W.E. Mesker, R. A. E. M Tollenaar, W. M. Meershoek‐Klein Kranenbarg, K. N. Gaarenstroom, C. M. R. Haekens, K. B. M. I. Keymeulen, J. Remmelzwaal, M. Piek‐den Hartog, E. J. T. Rutgers, C. Drukker, C. Lemstra, A. Prozee, J. de Vries, A. Stam, C. Bandel, I. Meijer, A. E. Dassen, S. Makineli, E. E. van Oers‐Hazelzet, A. J. Witkamp, K. E. Schenk, W. van der Eijk, M. B. E. Menke‐Pluijmers, J. de Droog‐Laane, B. A. Kortmann   +40 more
wiley   +1 more source

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, Volume 19, Issue 8, Page 2330-2347, August 2025.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Modified Radical Mastectomy

Annals of Surgery, 1972
Roche-Andre Bourque, Souheil Kandalaft, John L. Madden   +2 more
openaire   +4 more sources

Using Machine Learning to Improve Control for Confounding in the Dynamic Weighted Ordinary Least Squares Estimator of Optimal Adaptive Treatment Strategies

Biometrical Journal, Volume 67, Issue 4, August 2025.
ABSTRACT Estimating optimal adaptive treatment strategies (ATSs) can be done in several ways, including dynamic weighted ordinary least squares (dWOLS). This approach is doubly robust as it requires modeling both the treatment and the response, but only one of those models needs to be correctly specified to obtain a consistent estimator. For estimating
Kossi Clément Trenou, Miceline Mésidor, Aida Eslami, Hermann Nabi, Caroline Diorio, Denis Talbot   +5 more
wiley   +1 more source

The Identification of Novel Prognostic and Predictive Biomarkers in Breast Cancer via the Elucidation of Tumor Ecotypes Using Ecotyper

Cancer Innovation, Volume 4, Issue 4, August 2025.
A novel breast cancer subtyping based on intra‐tumoral microenvironment heterogeneity predicts prognosis and immunotherapy response. The CE2 subtype, in particular, is linked to the worst outcomes and the most significant immunotherapy benefits, with distinct cellular and molecular features mediated by hypoxia.
Feng Du, Jie Ju, Fangchao Zheng, Songlin Gao, Peng Yuan   +4 more
wiley   +1 more source

Radical Mastectomy for Mammary Carcinoma

Annals of Surgery, 1969
C. D. Haagensen, Edith Cooley
openaire   +10 more sources

Breast cancer in a transgender man

CA: A Cancer Journal for Clinicians, EarlyView.
Alison May Berner, Tristan Michael MacKenzie, Shirish Kulkarni, Chin Chong, Loren Schechter, Caroline Michie, Ole‐Petter Riksfjord Hamnvik   +6 more
wiley   +1 more source

Pilot Study of Cannabidiol for Treatment of Aromatase Inhibitor‐Associated Musculoskeletal Symptoms in Breast Cancer

Cancer Medicine, Volume 14, Issue 15, August 2025.
ABSTRACT Introduction Aromatase inhibitor (AI) therapy reduces breast cancer recurrence risk. However, some patients stop treatment early because of AI‐associated musculoskeletal symptoms (AIMSS). AIMSS is due in part to systemic inflammation. Cannabidiol (CBD) has anti‐nociceptive and anti‐inflammatory properties, making it a potential treatment ...
Nicole M. G. Fleege, Elise A. Miller, Kelley M. Kidwell, Zeb R. Zacharias, Jon Houtman, Kelly Scheu, Kathleen Kemmer, Kevin F. Boehnke, N. Lynn Henry   +8 more
wiley   +1 more source

A Multimodal Approach to the Early Treatment of a Facial Scar: A Case Report

Clinical Case Reports, Volume 13, Issue 8, August 2025.
ABSTRACT Facial scarring is associated with considerable psychosocial distress and can adversely affect overall quality of life. The combination of intralesional botulinum toxin injection and laser treatments in the early stage of wound healing markedly enhances scar appearance and improves cosmetic and psychological outcomes.
Jennifer Akl, Hamad El Hajj, Dima Jeha, Maya Habre   +3 more
wiley   +1 more source

Sonographic Correlations With Histological Grade and Biomarker Profiles in Breast Invasive Ductal Carcinoma

Cancer Reports, Volume 8, Issue 8, August 2025.
ABSTRACT Background Invasive ductal carcinoma (IDC), the most common breast cancer subtype, exhibits significant heterogeneity, limiting traditional prognostic markers. Molecular profiles improve precision, but imaging features may also reflect tumor biology.
Golnaz Moradi, Nasrin Ahmadinejad, Diana Zarei, Nahid Sadighi   +3 more
wiley   +1 more source