Molecular Oncology, EarlyView.Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi +14 more
wiley +1 more source
Enhancing Group Coaching Competencies in the National Diabetes Prevention Program: Evaluation of the Group Coaching Certificate Program. [PDF]
Am J Lifestyle MedSmith K +7 more
europepmc +1 more source
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Optimized Haptic Feedback and Natural Prehension System for Robotics and Virtual Reality Applications. [PDF]
Sensors (Basel)Hirel E +5 more
europepmc +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Clinical Accuracy of an Intraoral Scanner for Tooth Shade Selection Compared With a Spectrophotometer and Visual Matching: A Comparative Study. [PDF]
Clin Exp Dent ResBaqleh AS, Alhouri N.
europepmc +1 more source
Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Agreement of ocular biometry and evaluation of IOL calculation using a parameter‑hybrid strategy: a comparison of CASIA2, IOL Master 700, and OA2000 in cataract patients. [PDF]
BMC OphthalmolLin W +6 more
europepmc +1 more source
Master Melittologist Program on Pacific Region 1 National Wildlife Refuges : 2024 Season Report
In 2024 we marked the first year in a five year cooperative agreement between the Master Melittologist Oregon Bee Atlas Program (OBA) and the United States Fish and Wildlife Service (USFWS) for the inventory and monitoring of bees on National Wildlife ...
Best, Lincoln R. +2 more
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