Results 261 to 270 of about 5,450,138 (323)

Protocol for fabrication and utilization of the device for axon-cancer cell interaction testing. [PDF]

STAR Protoc
Velazquez-Quesada I, Allison K, Alizadeh V, Tüzel E, Gligorijevic B.   +4 more
europepmc   +1 more source

The cooperative regulation of miR‐221 by APE1 and AUF1 impacts p27Kip1 defining a miR signature relevant for cervical cancer

FEBS Open Bio, EarlyView.
A regulatory axis involving APE1, AUF1, and miR‐221 is proposed. Pri‐miR‐221 is processed by DROSHA and DICER to generate mature miR‐221, which targets p27Kip1 mRNA. APE1 and AUF1 compete for pre‐miR‐221 binding. Reduced APE1/AUF1 levels impair miR‐221 biogenesis, decrease p27Kip1 mRNA degradation, and promote cell cycle progression, chemoresistance ...
Matilde Clarissa Malfatti, Nicolò Gualandi, Gianluca Tell, Giulia Antoniali   +3 more
wiley   +1 more source

An Innovative Master Haptic Interface Employing Magnetorheological Fluids for Endovascular Catheterization. [PDF]

Sensors (Basel)
Zhang L, Huang S, Zuo J, Gu S, Xu L, Zhang Y, Jiang T.   +6 more
europepmc   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source

Ageing, Sex Differences, and REDs Risk in Endurance Runners: An Integrated Cross-Sectional Study Protocol. [PDF]

Sports (Basel)
Oreská Ľ, Kundeková B, Varga L, Stebelová K, Okuliarová M, Payer J, Sedliak M.   +6 more
europepmc   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

Protocol for validating computationally predicted splice-altering variants using full-length gene reporter assays. [PDF]

STAR Protoc
Lukes ME, Kiianitsa K, Widjaja A, Korvatska O.   +3 more
europepmc   +1 more source

Correlations among chemical and rheological aging indices/indicators of asphalt binder at high temperatures. [PDF]

Sci Rep
Taheri A, Khodaii A, Hajikarimi P.
europepmc   +1 more source

Handling of life-threatening situations in the context of hazard control and emergency response: Master Medic/Master Physician - an academic course. [PDF]

Front Psychiatry
Ziehr S, Merkt PH.
europepmc   +1 more source

UniGraphPTMs: a contrastive learning-enhanced universal framework for PTM site prediction via GNN and multimodal fusion. [PDF]

BMC Genomics
Lin Y, Wu J, Shen P, Yang S, Wang Y.
europepmc   +1 more source