Results 51 to 60 of about 771,856 (247)
Heart rate responses of a master athlete during ultra-endurance swimming
Aim: Swimming races outside swimming pools take place all over the world, but studies focusing on their physiological aspects are scarce. In fact, rules forbid any direct contact with swimmers during sanctioned events.
Renata Rodrigues Teixeira de Castro
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
"Jolted into Submission": Masters and Slaves in Paul Auster’s The Music of Chance and Mr. Vertigo [PDF]
In Paul Auster’s The Music of Chance and Mr. Vertigo, characters who resemble free individuals turn into slaves. In both novels, the major characters find meaning in life by willingly submitting to a superior power.
Nahid Fakhrshafaie , Jalal Sokhanvar
doaj
The Master-Slave Binary Opposition in African Fiction: An Advocacy of Slave Rebellion in André Brink’s An Instant in the Wind (2008) [PDF]
: This paper dealing with slave rebellion in André Brink’s An Instant in the Wind is analyzed through the lens of postcolonial studies, particularly its radical approach which emphasizes racial and cultural difference.
Souleymane TUO
doaj
The series, “Mastering your Fellowship”, provides examples of the question format encountered in the FCFP(SA) examination. The series aims to help family medicine registrars and their supervisors prepare for this examination. Model answers are available online.
Mergan Naidoo +3 more
openaire +12 more sources
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The First Experiments in Russia to Obtain a Degree in Philosophy
The paper attempts to identify the period in Russia when professional specialization in scientific and educational spheres is formed. To solve this problem, the author takes into account the institutional segment of philosophy in Russia, first of all ...
Vasily V. Vanchugov
doaj +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Time after time – circadian clocks through the lens of oscillator theory
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source

