Results 91 to 100 of about 3,627 (299)

Gut–Brain Axis Modulation by Short‐Chain Fatty Acids Exerts Disease‐Modifying Effects in a Murine Model of Drug‐Resistant Epilepsy

open access: yesAnnals of Neurology, EarlyView.
Objective Drug‐resistant epilepsy (DRE) remains a clinical challenge, as therapies modifying disease trajectory are lacking. Increasing evidence implicates gut microbiota dysbiosis in epilepsy pathophysiology, with short‐chain fatty acids (SCFAs) emerging as key microbial metabolites with neuroprotective and anti‐inflammatory properties.
Akash A. Bera   +16 more
wiley   +1 more source

Liposomal Delivery of L‐2‐Hydroxyglutarate for Targeting Epigenetic Dysregulation in Osteoarthritis

open access: yesAdvanced NanoBiomed Research, EarlyView.
Osteoarthritis involves cartilage degeneration, inflammation, and epigenetic dysregulation. A liposomal formulation of the TET1 inhibitor L‐2‐hydroxyglutarate to overcome rapid joint clearance was developed. The formulation showed good physicochemical properties, reduced inflammatory and catabolic gene expression in chondrocytes, and alleviated ...
Denise Murgia   +10 more
wiley   +1 more source

Predictors of Relapse and Post‐Relapse Outcomes After Frontline Blinatumomab in Philadelphia Chromosome‐Negative B‐ALL

open access: yes
American Journal of Hematology, EarlyView.
Sankalp Arora   +18 more
wiley   +1 more source

Culturological Approach in the Poetics of the Novel "Master and Margarita" M.A. Bulgakova

open access: yes, 2022
This article deals with the study of the moral-philosophical and mythopoetic understanding of a person, age and life in Mikhail Bulgakov's novel "The Master and Margarita", as well as the concepts of a cultural approach in the poetics of the ...
Batyrshina Zhumakul Kolmirzaevna
core  

New techniques for old bones: Morphometric and diffeomorphometric analysis of the bony labyrinth of the Reilingen and Ehringsdorf Neandertals

open access: yesThe Anatomical Record, EarlyView.
Abstract Neandertals are known to possess very distinctive traits in their bony labyrinth morphology, such as an inferiorly positioned posterior canal and a very low number of turns in the cochlea. Hence, the inner ear has been often used to assess the Neandertal status of fragmentary fossils.
Alessandro Urciuoli   +6 more
wiley   +1 more source

I Quaderni del Master Architettura | Storia | Progetto

open access: yes, 2007
La collana raccoglie una selezione di ricerche scientifiche e di progetti dei docenti e degli studenti del Master Architettura Storia ...
SEGARRA LAGUNES, MARIA MARGARITA
core  

“The Master and Margarita” as a “Strong” Text of Russian Culture: Translation Aspect

open access: yesRespectus Philologicus, 2015
The paper deals with the original inexhaustibility and translation multiplicity as new literary translation categories. Particular attention is paid to the information ambiguity of “strong” literary texts, which directly results in the generation of ...
Veronica Razumovskaya
doaj  

Investigating the Role of Type I Interferon Signaling on Muscle Disease Using Mouse Models

open access: yesArthritis &Rheumatology, EarlyView.
Objective Dysregulated type I interferon (IFN) signaling contributes to autoimmune myositis pathogenesis. We investigated the therapeutic effects of JAK inhibitors in two mouse models. We also examined how type I IFNs affect muscle vasculature. Methods Myositis was induced in major histocompatibility complex class I double transgenic ([TRE‐H‐2Kb (H ...
Rita Spathis   +11 more
wiley   +1 more source

Heroes in the novel of M. Bulgakow Master and Margarita.

open access: yes, 2016
Bakalářská práce se zabývá románem M. Bulgakova "Mistr a Markétka". Nejslavnější autorovo dílo vydané z pozůstalosti a je inspirováno atmosférou Moskvy 30. let 20. století.ObhájenoThis thesis deals with M. Bulgakov's novel "Master and Margarita".
Ševčenková, Alina
core  

The role of the Holy Fool in society as portrayed in the novels Maidenhair and The Master and Margarita [PDF]

open access: yes, 2014
textThis thesis examines the role of holy fool in society in the Russian novels Maidenhair [Venerin Volos] and The Master and Margarita [Masteri Margarita] by using Platonic philosophy from The Republic.
Shupala, Lindsay Anne
core  

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