Results 201 to 210 of about 2,796,043 (306)
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Programa de Pós-Graduação em Geografia - Teses Defendidas 1996 - Instituto de Geociências - Universidade Federal do Rio de Janeiro [PDF]
doaj
Viruses Infecting Cuban Honey Bees and Evolution of Deformed-Wing-Virus Variants. [PDF]
Hesketh-Best PJ +3 more
europepmc +1 more source
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Programa de Pós-Graduação em Geografia - Dissertações e Teses Defendidas 1997 - Instituto de Geociências - Universidade Federal do Rio de Janeiro [PDF]
doaj
Revocable and Traceable Decentralized ABE for P2P Networks. [PDF]
Gao D, Xu H, Qian S.
europepmc +1 more source
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source

