Results 81 to 90 of about 2,796,043 (306)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
ERASMUS Master of Science in Health Informatics
, 1997 Health Informatics is an emerging and important multi-disciplinary field that involves not only Informatics but also Medicine, Nursing, Engineering, Biology and other related subjects. A coordination of this field at a postgraduate level becomes important now in Europe where other European Community programs such as the “Telematics for Health
Diomidus, M., Mantas, J.
openaire +2 more sources
The bunheads are dead: Discovering high tech, high touch opportunities in Library and Information Science [PDF]
, 2008 Conjure up a picture of today\u27s librarian, and you are likely to be wrong. Professional librarians are information analysts, freedom of information and protection of privacy officers, family literacy specialists, Internet trainers, teen specialists ...
Garner, C., Haycock, Ken
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Investigations into feline (Felis catus) palatability : a thesis presented in partial fulfilment of the requirements for the degree of Master of Science in Nutritional Science at Massey University [PDF]
, 2004 Due to the finicky nature of the domestic cats' feeding habits, palatability is a highly complex area of feline nutrition, but one which is vitally important, with pet owners today selecting a brand based on palatability rather than nutritional value ...
Rutherford, Shay Rebekah
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
A Functional Investigation of Self-mention in Soft Science Master Theses [PDF]
Journal of Applied Linguistics, 2016 This study is a quantitative and functional corpus-based study of self-mention in soft science Master theses. One important purpose of this study was to find out the functions of self-mention in soft science Master theses.
Somaye Afsari, Davud Kuhi
doaj
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
β‐TrCP overexpression enhances cisplatin sensitivity by depleting BRCA1
Molecular Oncology, EarlyView.Low levels of β‐TrCP (Panel A) allow the accumulation of BRCA1 and CtIP, which facilitate the repair of cisplatin‐induced DNA damage via homologous recombination (HR) and promote tumor cell survival. In contrast, high β‐TrCP expression (Panel B) leads to BRCA1 and CtIP degradation, impairing HR repair, resulting in persistent DNA damage and apoptosis ...
Rocío Jiménez‐Guerrero +8 more
wiley +1 more source