Results 81 to 90 of about 180,130,499 (289)
Proceedings of the Arizona-Nevada Academy of Science, Volume 19 (1984)
, 1984 TWENTY EIGHTH ANNUAL MEETING / April 7, 1984 / Joint Meeting with the Pacific Division of the American Association for the Advancement of Science / Participating Societies: Arizona Junior Academy of Science, American Water Resources Association ...
Arizona-Nevada Academy of Science
core +2 more sources
Satisfaction of Postgraduate Students of Kerman University of Medical Sciences Iran with their Training Program and Campus Facilities [PDF]
Strides in Development of Medical Education, 2015 Background & Objective: Higher education and postgraduate programs characterize one of the key components of human development in any country The present study was carried out at Kerman University of Medical Sciences Iran with the aim of investigating ...
Ali Akbar Haghdoost +4 more
doaj
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Proceedings of the Arizona-Nevada Academy of Science, Volume 05 (1969)
, 1969 THIRTEENTH ANNUAL MEETING / April 18-19, 1969 / Joint Meeting with the Arizona Academy of Science, Psi Chi National Honor Society in Psychology, National Science Teachers Association, Society of American Foresters, and Southwestern Interagency Fire ...
Arizona-Nevada Academy of Science
core +2 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
FEBS Letters, EarlyView.Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas +4 more
wiley +1 more source
Information Management Policy - King Abdullah University of Science and Technology
, 2011 Records, Information and Archies Management Policy of King Abdullah University of Science and TechnologyRecords, Information and Archives Management Policy of King Abdullah University of Science and ...
King Abdullah University of Science and Technology
core
Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics
FEBS Letters, EarlyView.Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt +8 more
wiley +1 more source