Results 151 to 160 of about 1,912,044 (327)

Investigation of relationships through which biodynamic growing practices affect plant growth and nutrient composition : a thesis presented in partial fulfilment of the requirements of the degree of Master of Science in Soil Science at Massey University [PDF]

open access: yes, 2003
Author also known as Gillian Leslie ColeMore research attention has been paid to development of indicators of soil quality in relation to environmental sustainability than to food quality.
Bacchus, Gill
core  

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Teaching Translational Research to Medical Students: The New York University School of Medicine's Master's of Science in Clinical Investigation Dual‐Degree Program

open access: yesClinical and Translational Science, 2015
Jennifer Gillman   +7 more
semanticscholar   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

SPRU - Science and Technology Policy Research 40th Aniversary as a World Leader in Research, Consultancy and Teaching in Science, Technology and Innovation Policy

open access: yesJournal of Technology Management & Innovation, 2006
The following video shows Dr. Paul Nightingale, Senior Lecturer form Science Policy Research Unit (SPRU) University of Sussex, guest lecturer in the Technology Management Master Degree Program at University of Talca dictate the seminar called "SPRU ...
J. Technol. Manag. Innov.
doaj  

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

open access: yesMolecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande   +11 more
wiley   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

Issues and trends on sustainable transportation: the case of Brazilian cities (2003-2010)

open access: yesBrazilian Journal of Operations & Production Management, 2014
Brazilian transport system accounts for negative externalities in terms of energy consumption, carbon dioxide, local pollution emissions, social costs and infrastructure expenditures. These elements results on unsustainable mobility system.
Marcelo Sampaio Dias Maciel   +2 more
doaj  

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

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