Results 41 to 50 of about 308,319 (306)
Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions
FEBS Letters, EarlyView.Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf +6 more
wiley +1 more source
JPPPF: Jurnal Penelitian & Pengembangan Pendidikan Fisika, 2015 This research aims to increase student mastery of concepts, mastery of science process skills increase student mastery of concepts and relationships of students with his science process skills as applied to problem based learning model instruction in ...
Adam Malik
doaj +1 more source
Multimedia Interaktif Dalam Pembelajaran Konsep Listrik Bagi Calon Guru [PDF]
, 2015 There are many abstract concepts in physics. This raises its own difficulties in learning physics. The difficulty in teaching abstract concepts can be solved using computer technology.
Gunawan, G. (Gunawan) +2 more
core
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Pengaruh Keterampilan Berkomunikasi Sains Terhadap Penguasaan Konsep Fisika Siswa [PDF]
, 2013 Communication skills influence of science on students' mastery of physics concepts in a static fluid material, especially static fluid, which requires the student's ability to perform trial and analyze experimental results in order to assist them in ...
Pujiati, P. (Pujiati) +2 more
core
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Jurnal Kependidikan, 2017 Mastery of concepts is part of the important thinking skills dominated by students to be developed. Mastery of biological concepts held by students is still low.
Dewi Seprianingsih
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Relationship Between Students' Concept Mastery and the Ability to Assess Source Credibility Through Problem Based Learning in Environmental Pollution Concept [PDF]
, 2018 The aim of this research was to reveal a relationship between students' concepts mastery on the matter of environmental pollution with the ability to assess the credibility of the source through problem-based learning.
Kusumastuti, M. N. (Mimin) +2 more
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source