Host and habitat shape ectoparasite diversity on Mastomys natalensis and Mastomys coucha (Muridae) [PDF]
ParasitologyMastomys natalensis and M. coucha are commensal rodent species endemic to Africa. A recent taxonomic revision within Mastomys leaves the parasite–host list of M. natalensis questionable and that of M. coucha incomplete. The current study aimed to develop
Alyssa J. Little +5 more
doaj +7 more sources
Comparative Genomic Characterization of the Multimammate Mouse Mastomys coucha [PDF]
Molecular Biology and Evolution, 2019 Mastomys are the most widespread African rodent and carriers of various diseases such as the plague or Lassa virus. In addition, mastomys have rapidly gained a large number of mammary glands.
Aaron Hardin +2 more
exaly +9 more sources
Establishment of an Immortalized Skin Keratinocyte Cell Line Derived from the Animal Model Mastomys coucha. [PDF]
PLoS ONE, 2016 In the present report we describe the establishment of a spontaneous immortalized skin keratinocyte cell line derived from the skin of the multimammate rodent Mastomys coucha.
Daniel Hasche +5 more
doaj +6 more sources
Geospatial Modelling and Univariate Analysis of Commensal Rodent-Borne Cestodoses: The Case of Invasive spp. of Rattus and Indigenous Mastomys coucha From South Africa [PDF]
Frontiers in Veterinary Science, 2021 Poor socio-economic and unsanitary conditions are conducive to commensal rodent infestations, and these conditions are widespread in South Africa. Cestode species of zoonotic interest are highly prevalent in commensal rodents, such as invasive Rattus ...
Rolanda S. Julius +4 more
doaj +4 more sources
Immunization with Brugia malayi Myosin as Heterologous DNA Prime Protein Boost Induces Protective Immunity against B. malayi Infection in Mastomys coucha. [PDF]
PLoS ONE, 2016 The current control strategies employing chemotherapy with diethylcarbamazine, ivermectin and albendazole have reduced transmission in some filaria-endemic areas, there is growing interest for complementary approaches, such as vaccines especially in ...
Jyoti Gupta +2 more
doaj +3 more sources
Immunization of Mastomys coucha with Brugia malayi recombinant trehalose-6-phosphate phosphatase results in significant protection against homologous challenge infection. [PDF]
PLoS ONE, 2013 Development of a vaccine to prevent or reduce parasite development in lymphatic filariasis would be a complementary approach to existing chemotherapeutic tools.
Susheela Kushwaha +3 more
doaj +3 more sources
Mastomys Species as Model Systems for Infectious Diseases [PDF]
Viruses, 2019 Replacements of animal models by advanced in vitro systems in biomedical research, despite exceptions, are currently still not satisfactory in reproducing the whole complexity of pathophysiological mechanisms that finally lead to disease.
Daniel Hasche, Frank Rösl
doaj +3 more sources
Next generation L2-based HPV vaccines cross-protect against cutaneous papillomavirus infection and tumor development [PDF]
Frontiers in Immunology, 2022 Licensed L1-VLP-based immunizations against high-risk mucosal human papillomavirus (HPV) types have been a great success in reducing anogenital cancers, although they are limited in their cross-protection against HPV types not covered by the vaccine ...
Melinda Ahmels +10 more
doaj +2 more sources
Isoforms of the Papillomavirus Major Capsid Protein Differ in Their Ability to Block Viral Spread and Tumor Formation [PDF]
Frontiers in Immunology, 2022 Notably, the majority of papillomaviruses associated with a high cancer risk have the potential to translate different isoforms of the L1 major capsid protein. In an infection model, the cutaneous Mastomys natalensis papillomavirus (MnPV) circumvents the
Daniel Hasche +7 more
doaj +2 more sources
Expression of different L1 isoforms of Mastomys natalensis papillomavirus as mechanism to circumvent adaptive immunity [PDF]
eLife, 2020 Although many high-risk mucosal and cutaneous human papillomaviruses (HPVs) theoretically have the potential to synthesize L1 isoforms differing in length, previous seroepidemiological studies only focused on the short L1 variants, co-assembling with L2 ...
Yingying Fu +11 more
doaj +2 more sources