Results 41 to 50 of about 506 (161)

Cell Fate Regulation upon DNA Damage: p53 Serine 46 Kinases Pave the Cell Death Road

BioEssays, Volume 41, Issue 12, December 2019., 2019
Phosphorylation of p53 at Serine 46 drives the apoptotic and ferroptotic cell death response upon severe, irreparable DNA damage. This review summarizes and discusses how the p53 Ser46 phospho‐mark is wired to the cell death response, which kinases are setting this deadly phospho‐mark, as well as its evolutionary conservation and deregulation in human ...
Magdalena C. Liebl, Thomas G. Hofmann
wiley   +1 more source

Seasonal diet and numbers of prey consumed by Cape foxes Vulpes chama in South Africa

Wildlife Biology, Volume 20, Issue 3, Page 190-195, June 2014., 2014
The Cape fox Vulpes chama is one of the least studied Vulpes species, and little is known about their diet. By analyzing contents of scats, we determined the seasonal diet of Cape foxes on Benfontein Game Farm (BGF) in South Africa, and determined the biomass and number of rodents consumed.
Unn Klare, Jan F. Kamler, David W. Macdonald   +2 more
wiley   +1 more source

Comparative phylogeography of parasitic Laelaps mites contribute new insights into the specialist-generalist variation hypothesis (SGVH)

BMC Evolutionary Biology, 2018
Background The specialist-generalist variation hypothesis (SGVH) in parasites suggests that, due to patchiness in habitat (host availability), specialist species will show more subdivided population structure when compared to generalist species.
Conrad A. Matthee, Adriaan Engelbrecht, Sonja Matthee   +2 more
doaj   +1 more source

Evaluation of Halogenated Coumarins for Antimosquito Properties

The Scientific World Journal, Volume 2014, Issue 1, 2014., 2014
Mosquitoes are the major vectors of parasites and pathogens affecting humans and domestic animals. The widespread development of insecticide resistance and negative environmental effects of most synthetic compounds support an interest in finding and developing alternative products against mosquitoes.
Venugopala K. Narayanaswamy, Raquel M. Gleiser, Kabange Kasumbwe, Bandar E. Aldhubiab, Mahesh V. Attimarad, Bharti Odhav, Valdir Cechinel Filho   +6 more
wiley   +1 more source

Cofactor Independent Phosphoglycerate Mutase of Brugia malayi Induces a Mixed Th1/Th2 Type Immune Response and Inhibits Larval Development in the Host

BioMed Research International, Volume 2014, Issue 1, 2014., 2014
Lymphatic filariasis is a major debilitating disease, endemic in 72 countries putting more than 1.39 billion people at risk and 120 million are already infected. Despite the significant progress in chemotherapeutic advancements, there is still need for other measures like development of an effective vaccine or discovery of novel drug targets.
Prashant K. Singh, Susheela Kushwaha, Ajay K. Rana, Shailja Misra-Bhattacharya, Amogh A. Sahasrabuddhe   +4 more
wiley   +1 more source

Coinfection with Erethizon dorsatum papillomavirus types 1 and 2 in pigmented papillomatous skin lesions of a North American porcupine in Germany

Veterinary Record Case Reports, Volume 13, Issue 3, September 2025.
Abstract We present a case of a coinfection with two papillomaviruses—Erethizon dorsatum papillomavirus types 1 and 2 (EdPV1/2) in a North American porcupine housed in a German zoo. The animal exhibited exophytic black papules on the skin of the face and legs.
Anna Sophie Ramsauer, Dimitri Widmer, Eva Ziemmsen, Eva Ludwig, Kurt Tobler   +4 more
wiley   +1 more source

Recent Advances on the Use of Biochemical Extracts as Filaricidal Agents

Evidence-Based Complementary and Alternative Medicine, Volume 2013, Issue 1, 2013., 2013
Lymphatic filariasis is a parasitic infection that causes a devastating public health and socioeconomic burden with an estimated infection of over 120 million individuals worldwide. The infection is caused by three closely related nematode parasites, namely, Wuchereria bancrofti, Brugia malayi, and B.
Nazeh M. Al-Abd, Zurainee Mohamed Nor, Abdulelah H. Al-Adhroey, Anwar Suhaimi, S. Sivanandam, Yew-Min Tzeng   +5 more
wiley   +1 more source

Establishing enzyme immunoassays for quantifying fecal glucocorticoid metabolites in six southern African rodents using biological and physiological stimuli

Frontiers in Conservation Science
IntroductionGlobal landscape transformations and increased resource use are leading to an overall decline in ecosystem health and natural habitat quality.
Mmatsawela Ramahlo, Mmatsawela Ramahlo, Michael J. Somers, Daniel W. Hart, André Ganswindt   +4 more
doaj   +1 more source

In Vitro Activity of Geldanamycin Derivatives against Schistosoma japonicum and Brugia malayi

Journal of Parasitology Research, Volume 2010, Issue 1, 2010., 2010
Geldanamycin (GA) is a benzoquinone‐containing ansamycin that inhibits heat shock protein 90. GA derivatives are being evaluated as anti‐neoplastic agents, but their utility against parasites whose heat shock proteins (Hsps) have homology with human Hsp90 is unknown.
David Wenkert, Bernadette Ramirez, Yuehai Shen, Michael A. Kron, Nirbhay Kumar   +4 more
wiley   +1 more source

Systematics and biogeography of the genus Mastomys (Rodentia: Muridae) occurring in Namibia and adjacent countries [PDF]

, 2016
Das Ziel dieser Studie war, die Anzahl der Mastomys-Arten und ihrer geographischen Verbreitung in Namibia und Teilen von Botswana und Angola zu bestimmen.
Eiseb, Seth Johannes
core   +1 more source