Results 211 to 220 of about 23,257,412 (295)
KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan +16 more
wiley +1 more source
Match-related fatigue in basketball: A systematic review
This study aimed to systematically review fatigue responses following basketball match-play and during congested match schedules, considering performance, physiological, athlete-reported, and sleep-related outcomes.
P Sansone (21507035) +6 more
core
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner +14 more
wiley +1 more source
Comparison of Survival Outcomes between Radical Antegrade Modular Pancreatosplenectomy and Conventional Distal Pancreatosplenectomy for Pancreatic Body and Tail Cancer: Korean Multicenter Propensity Score Match Analysis. [PDF]
Kwon J +8 more
europepmc +1 more source
Beyond 'charting outcomes' in the radiation oncology match: analysis of self-reported applicant data. [PDF]
Jang S +4 more
europepmc +1 more source
Report on Shape Analysis and matching and Semantic matching
Report on existing shape analysis and matching algorithms and on existing semantic matching algorithms and their relevance and relationships to the ReAssembly, ReUnification and ReAssociation functionalities in GRAVITATE. These will be presented with respect to the user requirements uncovered in T2.2 and T2.3.
openaire +1 more source
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska +13 more
wiley +1 more source
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source

