Results 231 to 240 of about 3,191,923 (355)

A Statistical Analysis of Data from Controlled Comparative Trials with Matched Pairs on TNM Classification for Lung Cancer by Different Diagnoses

, 1980
Nobuo Yamashita
openalex   +2 more sources

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Weekend endoscopic retrograde cholangiopancreatography has similar outcomes as weekday procedures-a propensity score match analysis of the Hungarian ERCP Registry. [PDF]

Ther Adv Gastroenterol
Tajti M, Pécsi D, Mátrai P, Gódi S, Hegyi P, Szentesi A, Altorjay I, Bakucz T, Orbán-Szilágyi Á, Szepes Z, Patai Á, Gyökeres T, Fejes R, Dubravcsik Z, Vincze Á, Czakó L.   +15 more
europepmc   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Long-term results of edge-to-edge and neochordal mitral repair for isolated anterior leaflet lesion: a propensity match analysis. [PDF]

Eur J Cardiothorac Surg
Zancanaro E, Carino D, Lorusso R, Del Forno B, Lapenna E, Sala A, Ascione G, Scarale MG, Nonis A, Castiglioni A, Alfieri O, Maisano F, De Bonis M.   +12 more
europepmc   +1 more source

Applicant Perspective on the 2021 Ophthalmology Residency Cycle - A Post-Match Analysis

, 2022
Nirmalan A, Baiyasi A, Jassal J, Kasetty V, Goldman D.   +4 more
europepmc   +1 more source

Worst case scenario match analysis and contextual variables in professional soccer players: a longitudinal study. [PDF]

Biol Sport, 2020
Oliva-Lozano JM, Rojas-Valverde D, Gómez-Carmona CD, Fortes V, Pino-Ortega J.   +4 more
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Robotic Surgery in Severely Obese Frail Patients for the Treatment of Atypical Endometrial Hyperplasia and Endometrial Cancer: A Propensity-Match Analysis at an ESGO-Accredited Center. [PDF]

Cancers (Basel)
Arcieri M, Paparcura F, Giorgiutti C, Taliento C, Bogani G, Driul L, Greco P, Ercoli A, Chiantera V, Fanfani F, Fagotti A, Scambia G, Mariani A, Restaino S, Vizzielli G.   +14 more
europepmc   +1 more source