Results 51 to 60 of about 227,065 (305)

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Comparison of bioactive coils and bare platinum coils for treatment of intracranial aneurysms: a matched-pair analysis Clinical article

, 2010
Object. The primary goal of this matched-pair analysis was to evaluate the durability of the treatment results with Cerecyte coils in comparison with that of bare platinum coils in terms of angiographic occlusion rates at follow ...
Ertugrul, Ozgur, GEYİK, SERDAR, Cekirge, H. Saruhan, Geyik, PINAR, Saatci, Isil, Yavuz, Kivilcim   +5 more
core   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Paper 83: Clinical Outcomes of ACL Reconstruction vs ACL Repair: A Matched-Pair Analysis

Orthopaedic Journal of Sports Medicine, 2022
Objectives: Renewed interest in ACL repair is supported by promising early results from case series. However, comparative studies are currently lacking.
Alexandre Ferreira, Alessandro Carrozzo, Sylvain Guy MD, Thais Vieira, Johannes Barth, Bertrand Sonnery-Cottet MD, Adnan Saithna MD, FRCS   +6 more
doaj   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Result of univariable analysis by Mantel-Haenszel matched pair analysis of the possible risk factors associated with the risk of AIV H9N2 infection among commercial poultry farms.

, 2015
*P-value based on Wald statisticResult of univariable analysis by Mantel-Haenszel matched pair analysis of the possible risk factors associated with the risk of AIV H9N2 infection among commercial poultry farms.
Sue Welburn (333830), Mamoona Chaudhry (702605), Michael Thrusfield (651761), Barend MdeC. Bronsvoort (702607), Hamad B. Rashid (702606)   +4 more
core   +1 more source

Benchmarking Safety Indicators of Surgical Treatment of Brain Metastases Combined with Intraoperative Radiotherapy: Results of Prospective Observational Study with Comparative Matched-Pair Analysis

, 2022
Intraoperative radiotherapy (IORT) of the operative cavity for surgically treated brain metastasis (BM) has gained increasing prominence with respect to improved local tumor control.
Anna-Laura Potthoff, Frederic Carsten Schmeel, David Koch, Alexander Radbruch, Valeri Borger, Leonard Christopher Schmeel, Matthias Schneider, Erdem Güresir, Ulrich Herrlinger, Frank A. Giordano, Jasmin A. Holz, Hartmut Vatter, Niklas Schäfer, Stephan Garbe, Motaz Hamed, Davide Scafa, Muriel Heimann, Patrick Schuss, Gustavo R. Sarria, Julian P. Layer   +19 more
core   +1 more source

Clinical outcomes and dialysate calcium concentrations in Chinese patients on maintenance hemodialysis: a retrospective cohort study

Renal Failure
Background The appropriate concentration of dialysate calcium (DCa) for maintenance hemodialysis (MHD) patients remains a subject of ongoing debate. The relationship between DCa concentration and patient outcomes is not yet well established.
Yurong Pan, Yunhan He, Yunyan Murong, Juan Xu, Wenqin Yang, Wenyan Guo, Jianlin Jian, Haiwen An, Yanlin Li, Qingxiu Huang, Linna Liu   +10 more
doaj   +1 more source

Diversity and complexity in neural organoids

FEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

When Does It Pay to Break the Matches for Analysis of a Matched-Pairs Design? [PDF]

Biometrics, 1992
Two methods of analysis are compared to estimate the treatment effect of a comparative study where each treated individual is matched with a single control at the design stage. The usual matched-pairs analysis accounts for the pairing directly in its model, whereas regression adjustment ignores the matching but instead models the pairing using a set of
H S, Lynn, C E, McCulloch
openaire   +2 more sources