Results 71 to 80 of about 1,198,098 (316)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reasoning about Record Matching Rules [PDF]

open access: yes, 2009
To accurately match records it is often necessary to utilize the semantics of the data. Functional dependencies (FDs) have proven useful in identifying tuples in a clean relation, based on the semantics of the data. For all the reasons that FDs and their
Li, Jianzhong   +3 more
core  

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

The Big Match and the Paris Match [PDF]

open access: yes, 2003
In this paper we discuss the most typical and illustrative examples in stochastic game theory: the big match and a non-zero-sum extension thereof. These big match examples have played key roles in the development of stochastic game theory and we shall therefore examine them in some detail.keywordspure strategystationary strategystochastic gamerepeated ...
openaire   +2 more sources

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Difference matching

open access: yes, 1992
Difference matching is a generalization of first-order matching where terms are made identical both by variable instantiation and by structure hiding. After matching, the hidden structure may be removed by a type of controlled rewriting, called rippling, that leaves the rest of the term unaltered.
Basin, D., Walsh, T.
openaire   +3 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Median Stable Matching [PDF]

open access: yes
We define the median stable matching for two-sided matching markets with side payments and prove constructively that it exists.
Michael Schwarz, M. Bumin Yenmez
core  

Marker-free Automatic Matching of Range Data [PDF]

open access: yes, 2005
Matching of multiple views is often addressed in 3D-model generation and is normally a two-stage process consisting of a coarse and a fine matching stage.
Liu, Rui   +3 more
core  

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