Results 71 to 80 of about 1,383,780 (316)

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

open access: yesFEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Matching Polytons [PDF]

open access: yesThe Electronic Journal of Combinatorics, 2019
Hladký, Hu, and Piguet [Tilings in graphons, preprint] introduced the notions of matching and fractional vertex covers in graphons. These are counterparts to the corresponding notions in finite graphs.  Combinatorial optimization studies the structure of the matching polytope and the fractional vertex cover polytope of a graph.
Martin Dolezal, Jan Hladký
openaire   +5 more sources

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Reasoning about Record Matching Rules [PDF]

open access: yes, 2009
To accurately match records it is often necessary to utilize the semantics of the data. Functional dependencies (FDs) have proven useful in identifying tuples in a clean relation, based on the semantics of the data. For all the reasons that FDs and their
Li, Jianzhong   +3 more
core  

A New, Score-Based Multi-Stage Matching Approach for Road Network Conflation in Different Road Patterns

open access: yesISPRS International Journal of Geo-Information, 2019
Road-matching processes establish links between multi-sourced road lines representing the same entities in the real world. Several road-matching methods have been developed in the last three decades.
Müslüm Hacar, Türkay Gökgöz
doaj   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

Multi-Image Robust Alignment of Medium-Resolution Satellite Imagery

open access: yesRemote Sensing, 2018
This paper describes an automatic multi-image robust alignment (MIRA) procedure able to simultaneously co-register a time series of medium-resolution satellite images in a bundle block adjustment (BBA) fashion.
Marco Scaioni   +2 more
doaj   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

The Big Match and the Paris Match [PDF]

open access: yes, 2003
In this paper we discuss the most typical and illustrative examples in stochastic game theory: the big match and a non-zero-sum extension thereof. These big match examples have played key roles in the development of stochastic game theory and we shall therefore examine them in some detail.keywordspure strategystationary strategystochastic gamerepeated ...
openaire   +2 more sources

Identification of a Shiga toxin A‐derived peptide internalized into Gb3 receptor‐bearing cells via interaction with the Shiga toxin B subunit

open access: yesFEBS Letters, EarlyView.
The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi   +6 more
wiley   +1 more source

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